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Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

PLoS ONE(2020)10.1371/journal.pone.0227463Source: DataRank Database

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake is a research paper published in PLoS ONE (2020). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Open Access17 citations

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Enrichment:Funding (4 grants)Impact (FWCI 1.41)OA: goldTopics (70)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Kiera T. Blawn,Kathryn L. Kellohen,Beth M. Wiese ORCID,Vani Verkhovsky ORCID,Jared Wahl ORCID

Live enrichment

PubMed:32469979 PMC:PMC7259629 OpenAlex:https://openalex.org/W3032411770

National Institute of Neurological Disorders and Stroke

Grant: R01NS099292

Arizona Biomedical Research Commission

Grant: ABRC45952

NIDCR NIH HHS

Grant: F32 DE022499

National Institutes of Health

Grant: 5R01NS099292-03

Blood Brain Barrier and Migraine: Effect on Therapy

FWCI

1.41

Citation Percentile

0.8%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227463&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227463&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0227463

journalhttps://doi.org/10.1371/journal.pone.0227463

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32469979

Fields of Study

Migraine and Headache StudiesNeuroscience of respiration and sleepCerebrospinal fluid and hydrocephalus03 medical and health sciences0302 clinical medicineAnimalsBlood-Brain BarrierBrainCentral Nervous SystemCortical Spreading DepressionDisease Models, AnimalEndothelial CellsFemaleGene Expression RegulationHumansInjections, IntraperitonealMigraine with AuraRatsSodium-Hydrogen Exchanger 1SumatriptanTrigeminal Ganglion

MeSH Terms

Sodium-Hydrogen Exchanger 1AnimalsBlood-Brain BarrierBrainCentral Nervous SystemDisease Models, AnimalFemaleGene Expression RegulationHumansInjections, IntraperitonealTrigeminal GanglionCortical Spreading DepressionSumatriptanMigraine with AuraEndothelial CellsRats

Keywords

SumatriptanBlood–brain barrierPharmacologyCentral nervous systemSpinal trigeminal nucleusNeuroscienceChemistryMedicineAnesthesiaEndocrinologyInternal medicineBiologyAgonistNociceptionReceptorSodium-Hydrogen Exchanger 1ScienceQCortical Spreading DepressionMigraine with AuraRBrainEndothelial CellsRatsDisease Models, AnimalGene Expression RegulationTrigeminal GanglionBlood-Brain BarrierAnimalsHumansFemaleInjections, IntraperitonealResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake

FAIR Checklist

Authors (11)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)