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Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage

PLoS ONE(2020)10.1371/journal.pone.0237759Source: DataRank Database

Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage is a research paper published in PLoS ONE (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.30)OA: goldTopics (64)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Ramya Parasuram,Jacob V. Layer,Brendan D. Price ORCID,Nealia C. House ORCID

Live enrichment

PubMed:33332350 PMC:PMC7746297 OpenAlex:https://openalex.org/W3112689730

National Cancer Institute

Grant: CA93602

National Cancer Institute

Grant: CA177884

NCI NIH HHS

Grant: R01 CA093602

NCI NIH HHS

Grant: R01 CA177884

National Institutes of Health

Grant: 5R01CA177884-03

Nucleosome Dynamics and the Repair of DNA Damage

National Institutes of Health

Grant: 5R01CA093602-04

Functional Analysis of the Ataxia Telangiectasia Protein

FWCI

0.30

Citation Percentile

0.5%

Citation Trend

2021

2022

2023

2024

2025

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0237759&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0237759&type=printable

journalhttps://doi.org/10.1371/journal.pone.0237759

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33332350

repositoryhttp://europepmc.org/pmc/articles/PMC7746297

Fields of Study

CRISPR and Genetic EngineeringDNA Repair MechanismsAdvanced biosensing and bioanalysis techniques0301 basic medicine03 medical and health sciencesCRISPR-Cas SystemsCell LineChromatinClustered Regularly Interspaced Short Palindromic RepeatsDNADNA Breaks, Double-StrandedDNA DamageDNA RepairEndonucleasesGenomeHEK293 CellsHumansLightOxidative StressRNA, Guide, CRISPR-Cas Systems

MeSH Terms

RNA, Guide, CRISPR-Cas SystemsCell LineChromatinDNADNA DamageDNA RepairEndonucleasesHumansLightGenomeRNA, Guide, KinetoplastidaOxidative StressDNA Breaks, Double-StrandedHEK293 CellsClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems

Keywords

DNA damageChromatinCas9DNA repairDNABiologyCell biologyCRISPRChemistryGeneticsMolecular biologyGeneGenomeLightScienceQRRNA, Guide, CRISPR-Cas SystemsEndonucleasesCell LineOxidative StressHEK293 CellsMedicineHumansClustered Regularly Interspaced Short Palindromic RepeatsDNA Breaks, Double-StrandedCRISPR-Cas SystemsResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Life in Land

Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage

FAIR Checklist

Authors (4)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)