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Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

PLoS ONE(2020)10.1371/journal.pone.0242970Source: DataRank Database

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence is a research paper published in PLoS ONE (2020). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Scored on demand from live citation data

Open Access18 citations

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Enrichment:Funding (6 grants)Impact (FWCI 1.10)OA: goldTopics (62)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Mohammed Kanchwala ORCID,Shayna Thomas-Jardin ORCID,Amrit Sandhu,Preethi Kanumuri,Afshan F. Nawas ORCID

Live enrichment

PubMed:33326447 PMC:PMC7743957 OpenAlex:https://openalex.org/W3112702786

NCI NIH HHS

Grant: P50 CA140388

NCATS NIH HHS

Grant: UL1 TR001105

NCI NIH HHS

Grant: R01 CA184208

National Institutes of Health

Grant: 5R01CA184208-02

Genetic & Metabolic Dissection of the CaMKKbeta Signaling Axis in Prostate Cancer

National Institutes of Health

Grant: 4UL1TR001105-04

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)

National Institutes of Health

Grant: 5P50CA140388-03

Specimen Core

FWCI

1.10

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0242970&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0242970&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0242970

journalhttps://doi.org/10.1371/journal.pone.0242970

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33326447

Fields of Study

Prostate Cancer Treatment and ResearchImmunotherapy and Immune ResponsesCancer, Lipids, and Metabolism0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AndrogensBenzamidesCell SurvivalDrug SynergismHumansInterleukin-1MaleNitrilesPhenylthiohydantoinProstatic NeoplasmsReceptors, AndrogenTime FactorsTumor Necrosis Factor-alphaSignal TransductionIntracellular SpaceCell Line, TumorNF-kappa B p50 Subunit

Keywords

LNCaPEnzalutamideAndrogen receptorInflammationProstate cancerStromal cellCancer researchBiologyViability assayCytotoxic T cellGene silencingImmunologyEndocrinologyCell cultureCancerIn vitroGeneticsMaleTime FactorsCell SurvivalScienceIntracellular SpaceCell Line, TumorNitrilesPhenylthiohydantoinHumansTumor Necrosis Factor-alphaQRNF-kappa B p50 SubunitProstatic NeoplasmsDrug SynergismReceptors, AndrogenBenzamidesAndrogensMedicineResearch ArticleInterleukin-1Signal Transduction

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 0: Good health and well-being

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence

FAIR Checklist

Authors (10)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)