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Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction

PLoS ONE(2021)10.1371/journal.pone.0248941Source: DataRank Database

Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction is a research paper published in PLoS ONE (2021). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: goldTopics (64)IDs (PubMed)SDGs (2)

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Authors (11)

Jeffrey J. Lovelace ORCID,Joseph W. George,Mika Bessho,Dhananjaya Pal ORCID,Lucas R. Struble ORCID

Live enrichment

PubMed:33784323

National Institutes of Health

Grant: P30CA036727

Nebraska Department of Health and Human Services

Grant: 2018-11

Nebraska Department of Health and Human Services

Grant: 2017-08

Nebraska Department of Health and Human Services

Grant: 2015

U.S. Department of Education

Grant: P200A120231

National Institutes of Health

Grant: 5P30CA036727-23

CORE--Confocal Microscopy

goldLicense: cc-by

publisherhttps://doi.org/10.1371/journal.pone.0248941

publisherhttps://dx.plos.org/10.1371/journal.pone.0248941

repositoryhttps://doaj.org/article/61c7e66c5d784f338511623f59b276e2

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8009417

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009417

Fields of Study

0301 basic medicine03 medical and health sciencesApoptosisBRCA1 ProteinCell DeathCell Line, TumorCell SurvivalDNA DamageDNA RepairDoxorubicinFluorescenceHigh-Throughput Screening AssaysHomologous RecombinationHumansMitoxantroneNeoplasmsProtein BindingQuinacrineRad52 DNA Repair and Recombination ProteinReplication Protein ASmall Molecule Libraries

MeSH Terms

ApoptosisBRCA1 ProteinCell DeathCell Line, TumorCell SurvivalDNA DamageDNA RepairDoxorubicinFluorescenceHigh-Throughput Screening AssaysHomologous RecombinationHumansMitoxantroneNeoplasmsProtein BindingQuinacrineRad52 DNA Repair and Recombination ProteinReplication Protein ASmall Molecule Libraries

Keywords

DNA RepairCell SurvivalScienceApoptosisFluorescenceSmall Molecule LibrariesCell Line, TumorNeoplasmsReplication Protein AHumansHomologous RecombinationCell DeathBRCA1 ProteinQRHigh-Throughput Screening AssaysRad52 DNA Repair and Recombination ProteinDoxorubicinQuinacrineMedicineMitoxantroneResearch ArticleDNA DamageProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 16: 16. Peace & justice