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GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration

PLoS ONE(2021)10.1371/journal.pone.0251173Source: DataRank Database

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration is a research paper published in PLoS ONE (2021). On theSindex it has a DataRank of 0. It has been cited 23 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access23 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 1.19)OA: goldTopics (66)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Vincent A. Pham ORCID,Hayley W. S. Tsang,Mriganka Sur ORCID,Chloé Delépine ORCID

Live enrichment

PubMed:33951093 PMC:PMC8099055 OpenAlex:https://openalex.org/W3157841686

National Institute of Mental Health

Grant: R01MH085802

National Institutes of Health

Grant: 1R01MH085802-01A1

Mechanisms and Therapeutics for Rett Syndrome

Simons Center for the Social Brain

JPB Foundation, Picower Fellowship Program

FWCI

1.19

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0251173&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0251173&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0251173

journalhttps://doi.org/10.1371/journal.pone.0251173

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33951093

Fields of Study

Pluripotent Stem Cells ResearchHippo pathway signaling and YAP/TAZRenal and related cancers0301 basic medicine03 medical and health sciencesApoptosisBrainCell DifferentiationCell MovementCell ProliferationCell SurvivalCells, CulturedGlycogen Synthase Kinase 3 betaHumansInduced Pluripotent Stem CellsNeurogenesisOrganoidsPyridinesPyrimidines

MeSH Terms

Glycogen Synthase Kinase 3 betaBrainCell DifferentiationCell MovementCell SurvivalCells, CulturedHumansOrganoidsPyridinesPyrimidinesApoptosisCell ProliferationNeurogenesisInduced Pluripotent Stem Cells

Keywords

OrganoidProgenitor cellCell biologyBiologyEmbryonic stem cellInduced pluripotent stem cellNeurogenesisNeural stem cellCell growthCellular differentiationStem cellNeuroepithelial cellCell typeCellGeneticsGlycogen Synthase Kinase 3 betaCell SurvivalPyridinesScienceQInduced Pluripotent Stem CellsRBrainApoptosisCell DifferentiationOrganoidsPyrimidinesCell MovementMedicineHumansCells, CulturedResearch ArticleCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good health

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration

FAIR Checklist

Authors (4)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)