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Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway

PLoS ONE(2021)10.1371/journal.pone.0252541Source: DataRank Database

Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway is a research paper published in PLoS ONE (2021). On theSindex it has a DataRank of 0. It has been cited 11 times.

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Open Access11 citations

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Enrichment:Funding (4 grants)Impact (FWCI 1.21)OA: goldTopics (77)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Benigno C. Valdez ORCID,Yang Li ORCID,Seemanti Chakrabarti,Braham Dhillon ORCID,Sofronio P. Kalaw ORCID

Live enrichment

PubMed:34048499 PMC:PMC8162692 OpenAlex:https://openalex.org/W3165196678

National Institutes of Health

Grant: CA016672

NCI NIH HHS

Grant: P30 CA016672

National Institutes of Health

Grant: 3P30CA016672-41S4

Cancer Center Support (CORE) Grant

Department of Science and Technology

FWCI

1.21

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0252541&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0252541&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0252541

journalhttps://doi.org/10.1371/journal.pone.0252541

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34048499

Fields of Study

Fungal Biology and ApplicationsSilymarin and Mushroom PoisoningPhytochemistry and Bioactivity Studies0301 basic medicine0303 health sciences03 medical and health sciencesAcetylcysteineAgaricalesApoptosisCaspase 3Cell Line, TumorCell ProliferationG1 Phase Cell Cycle CheckpointsHematologic NeoplasmsHumansJNK Mitogen-Activated Protein KinasesMAP Kinase Kinase 4Membrane Potential, MitochondrialPlant ExtractsReactive Oxygen SpeciesSignal Transductionp38 Mitogen-Activated Protein KinasesGymnopilus purpureosquamulosus

MeSH Terms

AcetylcysteineAgaricalesHumansPlant ExtractsSignal TransductionApoptosisReactive Oxygen SpeciesHematologic NeoplasmsCell Line, TumorJNK Mitogen-Activated Protein Kinasesp38 Mitogen-Activated Protein KinasesMAP Kinase Kinase 4Cell ProliferationMembrane Potential, MitochondrialCaspase 3G1 Phase Cell Cycle Checkpoints

Keywords

ApoptosisCytotoxicityDNA fragmentationp38 mitogen-activated protein kinasesReactive oxygen speciesPeroxiredoxinAnnexinBiologyMolecular biologyCancer researchThioredoxinAnnexin A5KinaseMAPK/ERK pathwayChemistryProgrammed cell deathCell biologyBiochemistryOxidative stressEnzymeMembrane Potential, MitochondrialCaspase 3MAP Kinase Kinase 4Plant ExtractsScienceQRJNK Mitogen-Activated Protein KinasesG1 Phase Cell Cycle CheckpointsAcetylcysteineCell Line, TumorHematologic NeoplasmsMedicineHumansAgaricalesResearch ArticleCell ProliferationSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health

Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway

FAIR Checklist

Authors (8)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)