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Comparative use of CRISPR and RNAi to modulate integrin α3β1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic α3β1 functions are independent of global regulation of the transcriptome

PLoS ONE(2021)10.1371/journal.pone.0254714Source: DataRank Database

Comparative use of CRISPR and RNAi to modulate integrin α3β1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic α3β1 functions are independent of global regulation of the transcriptome is a research paper published in PLoS ONE (2021). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.61)OA: goldTopics (63)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Abibatou Ndoye ORCID,John M. Lamar ORCID,C. Michael DiPersio ORCID,James Kenney

Live enrichment

PubMed:34270616 OpenAlex:https://openalex.org/W3179662953

National Cancer Institute

Grant: R01CA129637

Susan G. Komen

Grant: CCR17477184

National Institutes of Health

Grant: 5R01CA129637-09

Integrin Regulation of Cancer Progression Through Alternative mRNA Splicing and Nonsense-Medidated Decay (NMD)

FWCI

0.61

Citation Percentile

0.6%

Citation Trend

2021

2023

2024

2025

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254714&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254714&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0254714

journalhttps://doi.org/10.1371/journal.pone.0254714

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34270616

Fields of Study

Cell Adhesion Molecules ResearchMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses0301 basic medicine03 medical and health sciences

MeSH Terms

Gene EditingRNA-SeqAnimalsCell MovementFemaleHumansLung NeoplasmsNeoplasm InvasivenessGene Expression Regulation, NeoplasticXenograft Model Antitumor AssaysRNA InterferenceIntegrin alpha3beta1Cell Line, TumorCell ProliferationMiceTranscriptomeCarcinogenesisCRISPR-Cas SystemsTriple Negative Breast NeoplasmsDatasets as Topic

Keywords

BiologyIntegrinRNA interferenceCancer researchMetastasisCarcinogenesisCell biologyGene expressionTranscriptomeCollagen receptorCRISPRCancerCellGeneRNAGeneticsLung NeoplasmsScienceDatasets as TopicTriple Negative Breast NeoplasmsMiceCell MovementCell Line, TumorAnimalsHumansNeoplasm InvasivenessRNA-SeqCell ProliferationGene EditingQRIntegrin alpha3beta1Xenograft Model Antitumor AssaysGene Expression Regulation, NeoplasticMedicineFemaleCRISPR-Cas SystemsResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being