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The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling

PLoS ONE(2021)10.1371/journal.pone.0256238Source: DataRank Database

The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling is a research paper published in PLoS ONE (2021). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.15)OA: goldTopics (53)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Alexander R. Terry ORCID,Adam D. Pierce,Michael C. Cavalier ORCID,Catherine Blaha,Kaylin A. Adipietro

Live enrichment

PubMed:34411141 PMC:PMC8376063 OpenAlex:https://openalex.org/W3195820473

National Institutes of Health

Grant: R01 CA107331

National Institutes of Health

Grant: F30 CA225058

National Institutes of Health

Grant: F30 CA228191

NIGMS NIH HHS

Grant: R01 GM129327

NCI NIH HHS

Grant: T32 CA154274

National Institutes of Health

Grant: 3R01CA107331-08S1

Restoration of Tumor Suppression Activity in Malignant Melanoma

National Institutes of Health

Grant: 1F30CA225058-01

Exploiting Metabolic Changes in HCC for Cancer Therapy

National Institutes of Health

Grant: 5F30CA228191-02

Elucidating the Mechanisms by which Hexokinase 2 Regulates Breast Cancer Metastasis

FWCI

0.15

Citation Percentile

0.4%

Citation Trend

2023

2024

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0256238&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0256238&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0256238

journalhttps://doi.org/10.1371/journal.pone.0256238

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34411141

Fields of Study

S100 Proteins and AnnexinsHeat shock proteins researchImmune Response and Inflammation0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Calcium-Binding ProteinsCytoplasmDoxycyclineHumansMelanomaSignal TransductionInterleukin-6Gene Expression Regulation, NeoplasticCyclic AMP Response Element-Binding ProteinRibosomal Protein S6 Kinases, 90-kDaCell Line, TumorSTAT3 Transcription FactorS100 Calcium Binding Protein beta Subunit

Keywords

Autocrine signallingMelanomaRibosomal s6 kinaseSTAT3Signal transductionPhosphorylationCREBCancer researchTranscription factorBiologyCell biologyCell cultureChemistryMolecular biologyBiochemistryP70-S6 Kinase 1PI3K/AKT/mTOR pathwayGeneSTAT3 Transcription FactorCytoplasmInterleukin-6ScienceQCalcium-Binding ProteinsRS100 Calcium Binding Protein beta SubunitRibosomal Protein S6 Kinases, 90-kDaGene Expression Regulation, NeoplasticCell Line, TumorDoxycyclineMedicineHumansCyclic AMP Response Element-Binding ProteinResearch Article

Sustainable Development Goals

SDG 3: 3. Good health