Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype

PLoS ONE(2022)10.1371/journal.pone.0263370Source: DataRank Database

In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype is a research paper published in PLoS ONE (2022). On theSindex it has a DataRank of 0.715. It has been cited 22 times, with 20 citing works in its 1-hop citation network.

N/A

0.715DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access22 citations · 20 citing works in its network

Download PDF

Cite:

Linked data & code

arrayexpress nct

Data availability

Repositories this paper deposited data in (declared in PubMed).

ClinicalTrials.govNCT02609932

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.43)OA: goldTopics (63)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 66%Citation Network 34%

Base Score Contribution

0.470

From this paper's citation signal

Citation Network Contribution

0.245

From 12 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 20 citers.

Efficacy and Safety of Interferon-Gamma in Chronic Granulomatous Disease: a Systematic Review and Meta-analysis
Journal of Clinical Immunology202219 citations40 referencesContributes 0.075
Evidence for antigen presentation by human neutrophils
Blood202436 citations94 referencesContributes 0.038
Utility of monocyte HLA-DR and rationale for therapeutic GM-CSF in sepsis immunoparalysis
Frontiers in Immunology202377 citations151 referencesContributes 0.029
Genotype-phenotype correlations in chronic granulomatous disease: insights from a large national cohort
Blood202411 citations95 referencesContributes 0.026
Interferon- γ and infectious diseases: Lessons and prospects
Science2024147 citations195 referencesContributes 0.026

Authors (9)

Natalie Briones ORCID,Angelina Baroffio ORCID,John R. Murphy ORCID,Alexander Tran ORCID,Katherine Gowan

Live enrichment

PubMed:35113934 PMC:PMC8812922 OpenAlex:https://openalex.org/W4210464309

NIH/NCATS

Grant: UL1TR002535

Horizon Therapeutics

Grant: unidentified

unidentified

National Institutes of Health

Grant: 3UL1TR002535-03S1

NIH Prior Approval Process Professional

Horizon Pharma

Stacy True Memorial Trust Fund

FWCI

1.43

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263370&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263370&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0263370

journalhttps://doi.org/10.1371/journal.pone.0263370

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35113934

Fields of Study

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmune Response and InflammationInflammasome and immune disorders0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

AdolescentAdultGene Expression RegulationGranulomatous Disease, ChronicHumansInterferon-gammaMiddle AgedNeutrophilsPhagocytosisPhenotypeSuperoxidesRespiratory BurstNADPH OxidasesNeopterinGene Expression ProfilingChemokine CXCL10Young AdultHealthy Volunteers

Keywords

Respiratory burstNADPH oxidaseImmunologyImmune systemSuperoxideInnate immune systemNeopterinBiologyInterferon gammaReceptorCytokinePhagocytosisChronic granulomatous diseaseGranulocyteInterferonReactive oxygen speciesCell biologyBiochemistryEnzymeAdultAdolescentNeutrophilsScienceGranulomatous Disease, ChronicInterferon-gammaYoung AdultSuperoxidesHumansGene Expression ProfilingQRNADPH OxidasesMiddle AgedHealthy VolunteersChemokine CXCL10PhenotypeGene Expression RegulationMedicineResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being