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Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1

PLoS ONE(2022)10.1371/journal.pone.0266993Source: DataRank Database

Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1 is a research paper published in PLoS ONE (2022). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.12)OA: goldTopics (42)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

James R. Lundblad,Stephen M. Smith ORCID,Xiaohua Wang ORCID

Live enrichment

PubMed:35857775 OpenAlex:https://openalex.org/W4286008659

Foundation for the National Institutes of Health

Grant: R01GM134110

U.S. Department of Veterans Affairs

Grant: BX002547

National Institutes of Health

Grant: 5R01GM134110-03

Sodium channel control of neuronal excitability

FWCI

0.12

Citation Percentile

0.4%

Citation Trend

2024

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0266993&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0266993&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0266993

journalhttps://doi.org/10.1371/journal.pone.0266993

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35857775

Fields of Study

Parathyroid Disorders and TreatmentsIon Transport and Channel RegulationMetabolism, Diabetes, and Cancer0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

CalciumHumansHypercalcemiaInfant, NewbornMutationReceptors, Calcium-SensingHyperparathyroidism, Primary

Keywords

Calcium-sensing receptorReceptorMutantHEK 293 cellsMutationWild typeTransfectionChemistryCalcium in biologyExtracellularMolecular biologyCell biologyBiologyEndocrinologyInternal medicineCalciumCalcium metabolismBiochemistryGeneMedicineScienceQRInfant, NewbornHyperparathyroidism, PrimaryHypercalcemiaHumansReceptors, Calcium-SensingResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being