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Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B’s antifungal efficacy in cryptococcosis

PLoS ONE(2024)10.1371/journal.pone.0308216Source: DataRank Database

Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B’s antifungal efficacy in cryptococcosis is a research paper published in PLoS ONE (2024). On theSindex it has a DataRank of 0. It has been cited 7 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.98)OA: goldTopics (61)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Mohamed N. Seleem ORCID,Nour M. Al-Kashef ORCID

Live enrichment

PubMed:39088434 PMC:PMC11293717 OpenAlex:https://openalex.org/W4401212180

National Institutes of Health

Grant: R01AI141439.

NIAID NIH HHS

Grant: R01 AI141439

National Institutes of Health

Grant: 5R01AI141439-04

Metabolic Assessment of Anti-Microbial Susceptibility within One Cell Cycle

FWCI

1.98

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0308216&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0308216&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0308216

journalhttps://doi.org/10.1371/journal.pone.0308216

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39088434

Fields of Study

Fungal Infections and StudiesAntifungal resistance and susceptibilityNail Diseases and Treatments0301 basic medicine03 medical and health sciencesAmphotericin BAntifungal AgentsHIV Protease InhibitorsAnimalsDrug SynergismCryptococcosisHumansCaenorhabditis elegansMicrobial Sensitivity TestsCryptococcus neoformansDrug Therapy, CombinationRitonavirCryptococcus

MeSH Terms

Amphotericin BAnimalsAntifungal AgentsCryptococcosisCryptococcusCryptococcus neoformansDrug SynergismDrug Therapy, CombinationHumansMicrobial Sensitivity TestsCaenorhabditis elegansHIV Protease InhibitorsRitonavir

Keywords

Amphotericin BCryptococcosisFluconazoleSaquinavirRitonavirLopinavirPharmacologyCryptococcusFlucytosineBiologyMicrobiologyMedicineImmunologyAntifungalViral loadHuman immunodeficiency virus (HIV)Antiretroviral therapyAntifungal AgentsScienceQRDrug SynergismHIV Protease InhibitorsMicrobial Sensitivity TestsCryptococcus neoformansAnimalsHumansDrug Therapy, CombinationCaenorhabditis elegansResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being