Single nucleus RNA sequencing of the cerebral cortex from genetically diverse inbred mouse strains reveals differences in pericyte and endothelial cell composition is a dataset published in PLoS ONE (2025). On theSindex it has a DataRank of 0.104, placing it in the top 78.1% of the data-sharing corpus. It has been cited 1 time. Its calibrated FAIR score is 63/100.
Ranks in the top 78% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“GSE263649”
The data availability statement provides the GEO accession number for the dataset.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
The repository is named as Gene Expression Omnibus (GEO).
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
The dataset identifier appears only in the body text (data availability statement) and not in the reference list.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
The statement points to a repository record with an accession number. [majority verdict 'yes' (4/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“In total, we analyzed 287,047 nuclei from 92 animals that included over 1.5 billion UMIs (S1 Table).”
The paper references S1 Table which itemizes the dataset summary.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
The data are deposited in a public repository with no stated precondition.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
No explicit access-level label is applied to the data; the route is described by action.
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are from mouse studies, not human subjects, and no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“The raw and processed sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database under accession number GSE263649.”
The paper states the data are deposited (available now) but does not specify how long they will persist. [majority verdict 'partial' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
The paper does not name a file format for the released data. [majority verdict 'no' (4/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“The study is reported in accordance with ARRIVE guidelines.”
The paper reports adherence to the ARRIVE guidelines, a manuscript reporting guideline.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“RRID:SCR_019060”
The paper includes an RRID for the UNC Neuroscience Microscopy Core, an identifier for a resource other than the study's own dataset. [majority verdict 'yes' (3/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No license is named for the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is given for the dataset.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“The metadata and scripts used for snRNAseq analysis are available in the GitHub page (https://github.com/jieunesther/CC_snRNAseq/).”— not found in the paper; verdict downgraded
The paper provides a GitHub URL for the scripts. [downgraded to 'partial' — no verifiable quote from the paper]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“J.P. is supported by grants from the National Institute of Child Health and Human Development (NICHD; T32HD040127).”
The paper gives grant number T32HD040127.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“All libraries were pooled and sequenced on an Illumina NovaSeq 6000-S4.”
The paper names the sequencing platform Illumina NovaSeq 6000.
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“In total, we analyzed 287,047 nuclei from 92 animals that included over 1.5 billion UMIs (S1 Table).”
The paper includes S1 Table inside the article defining the dataset summary. [majority verdict 'partial' (4/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.104
From this paper's citation signal
Citation Network Contribution
0
Citation network not refreshed for this result
This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.
Learn more about DataRank methodology →NICHD NIH HHS
Grant: T32 HD040127
National Institute of Neurological Disorders and Stroke
Grant: P30 NS045892
National Institute of Mental Health and Neurosciences
Grant: R01MH120229
Microscopy was performed at the UNC Neuroscience Microscopy Core
Grant: SCR_019060
National Institute of Neurological Disorders and Stroke
Grant: R01NS109304
National Institute of Environmental Health Sciences
Grant: R35ES028366
NIH-NICHD
Grant: P50 HD103573
National Institutes of Health
Grant: 5P50HD103573-03
Clinical Translational Research Center for Neurodevelopmental Disorders
National Institutes of Health
Grant: 5T32HD040127-05
Postdoctoral Research in Neurodevelopmental Disorders
National Institutes of Health
Grant: 5R01MH120229-05
UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypes
National Institutes of Health
Grant: 5P30NS045892-18
UNC Neuroscience Center Research Cores
National Institutes of Health
Grant: 5R35ES028366-04
Environmental-use chemicals that target pathways linked to autism and other neurodevelopmental disorders
National Institutes of Health
Grant: 5R01NS109304-02
CRISPR/Cas9-based gene therapy for Angelman syndrome
FWCI
0.38
Citation Percentile
0.6%
Citation Trend
Fields of Study
MeSH Terms
Keywords