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Polygenic associations with clinical and neuropathological trait heterogeneity across TDP-43 proteinopathies

PLoS ONE(2025)10.1371/journal.pone.0338398Source: DataRank Database

Polygenic associations with clinical and neuropathological trait heterogeneity across TDP-43 proteinopathies is a research paper published in PLoS ONE (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: goldTopics (24)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

David J. Irwin ORCID,Vivianna M. Van Deerlin ORCID,Eunran Suh,Edward B. Lee ORCID,Lauren Elman ORCID

Live enrichment

PubMed:41468379 PMC:PMC12752993 OpenAlex:https://openalex.org/W7117559782

National Institute on Aging

Grant: F32AG079618

National Institute on Aging

Grant: P01AG066597

National Institutes of Health

Grant: NS109260

National Institute of Neurological Disorders and Stroke

Grant: RF1NS145263

National Institute on Aging

Grant: P30AG072979

NINDS NIH HHS

Grant: R01 NS109260

FWCI

0.00

Citation Percentile

0.6%

goldLicense: cc-by

journalhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0338398&type=printable

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0338398&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0338398

journalhttps://doi.org/10.1371/journal.pone.0338398

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41468379

Fields of Study

Amyotrophic Lateral Sclerosis ResearchGenomics and Rare DiseasesGenetic Neurodegenerative Diseases

MeSH Terms

AgedAmyotrophic Lateral SclerosisDNA-Binding ProteinsFemaleHumansMaleMiddle AgedPhenotypeGenetic Predisposition to DiseaseMultifactorial InheritancePolymorphism, Single NucleotideGenome-Wide Association StudyTDP-43 Proteinopathies

Keywords

Genome-wide association studyAmyotrophic lateral sclerosisQuantitative trait locusTraitMultifactorial InheritanceFrontotemporal lobar degenerationFrontotemporal dementiaSingle-nucleotide polymorphism

Sustainable Development Goals

SDG 0: Good health and well-being