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An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing

PLoS Pathogens(2020)10.1371/journal.ppat.1008307Source: DataRank Database

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing is a research paper published in PLoS Pathogens (2020). On theSindex it has a DataRank of 0. It has been cited 15 times.

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Scored on demand from live citation data

Open Access15 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 1.32)OA: goldTopics (82)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Ahalya Balachandran,Peter K. Cheung ORCID,Ran Cheng ORCID,Qun Pan ORCID,Peter Stoilov ORCID

Live enrichment

PubMed:32069328 PMC:PMC7048317 OpenAlex:https://openalex.org/W3007015347

Canadian Institutes of Health Research

Grant: 158250

Canadian Institutes of Health Research

Grant: HOP-134065

National Institutes of Health

Grant: EY025536

Canadian Institutes of Health Research

Grant: Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarship

Government of Ontario

Grant: Ontario Graduate Scholarship

NEI NIH HHS

Grant: R01 EY025536

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1R01EY025536-01A1

Photoreceptor neuron specific alternative splicing of messenger RNA

National Health and Medical Research Council (NHMRC)

Grant: 1008307

Cellular effects of glucocerebrosidase (GBA) mutations in Lewy body diseases

FWCI

1.32

Citation Percentile

0.8%

Citation Trend

2020

2021

2022

2023

2024

goldLicense: cc-by

journalhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008307&type=printable

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008307&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1008307

journalhttps://doi.org/10.1371/journal.ppat.1008307

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32069328

Fields of Study

HIV Research and TreatmentRNA Research and SplicingRNA regulation and disease0301 basic medicine03 medical and health sciences0303 health sciencesAlternative SplicingGene ExpressionGene Expression Regulation, ViralHIV InfectionsHIV SeropositivityHIV-1HeLa CellsHumansMAP Kinase Kinase 1MAP Kinase Kinase Kinase 2MAP Kinase Signaling SystemRNA Processing, Post-TranscriptionalRNA SplicingRNA, ViralReceptors, G-Protein-CoupledSignal TransductionSmall Molecule LibrariesVirus Replicationtat Gene Products, Human Immunodeficiency Virus

MeSH Terms

HeLa CellsHIV SeropositivityHumansRNA Processing, Post-TranscriptionalRNA SplicingRNA, ViralVirus ReplicationSignal TransductionHIV-1HIV InfectionsGene ExpressionGene Expression Regulation, ViralAlternative SplicingMAP Kinase Signaling SystemReceptors, G-Protein-CoupledMAP Kinase Kinase 1MAP Kinase Kinase Kinase 2tat Gene Products, Human Immunodeficiency VirusSmall Molecule LibrariesHela Cells

Keywords

BiologyViral replicationRNARNA splicingGene expressionActivator (genetics)KinaseMolecular biologyMessenger RNACell biologyVirologyVirusReceptorGeneBiochemistryGene Expression Regulation, ViralQH301-705.5MAP Kinase Signaling SystemMAP Kinase Kinase 1HIV InfectionsMAP Kinase Kinase Kinase 2Virus ReplicationReceptors, G-Protein-CoupledSmall Molecule LibrariesHIV SeropositivityHumansBiology (General)RNA Processing, Post-TranscriptionalRC581-607Alternative SplicingHIV-1RNA, Viraltat Gene Products, Human Immunodeficiency VirusImmunologic diseases. AllergyResearch ArticleHeLa CellsSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing

FAIR Checklist

Authors (10)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)