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Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques

PLoS Pathogens(2020)10.1371/journal.ppat.1008487Source: DataRank Database

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques is a research paper published in PLoS Pathogens (2020). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)OA: goldTopics (36)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)SDGs (1)

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Authors (9)

Sanath Kumar Janaka ORCID,Katie R. Zarbock,Shelby L. O’Connor ORCID,Kristin Crosno ORCID,Saverio Capuano ORCID

Live enrichment

PubMed:32302364 PMC:PMC7190186

Foundation for the National Institutes of Health

Grant: AI098485

National Institutes of Health

Grant: AI095098

Foundation for the National Institutes of Health

Grant: AI121135

Foundation for the National Institutes of Health

Grant: P51OD011106

Foundation for the National Institutes of Health

Grant: HHSN261200800001E

NIAID NIH HHS

Grant: R01 AI121135

NIAID NIH HHS

Grant: R01 AI155163

CCR NIH HHS

Grant: HHSN261200800001C

NIAID NIH HHS

Grant: R01 AI098485

NIAID NIH HHS

Grant: R01 AI148379

NIAID NIH HHS

Grant: R37 AI095098

NIAID NIH HHS

Grant: R01 AI095098

National Institutes of Health

Grant: 5R01AI121135-05

Fcgamma receptor-mediated suppression of immunodeficiency virus replication

National Institutes of Health

Grant: 5R01AI095098-04

KIR and MHC Class I Immunogenetics in SIV Infection

National Institutes of Health

Grant: 3P51OD011106-60S1

Wisconsin National Primate Research Center Support

National Institutes of Health

Grant: 1R01AI098485-01A1

Lentiviral Resistance to Tetherin

goldLicense: cc-by

publisherhttps://storage.googleapis.com/plos-corpus-prod/10.1371/journal.ppat.1008487/2/ppat.1008487.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210217%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210217T071348Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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

publisherhttps://dx.plos.org/10.1371/journal.ppat.1008487

repositoryhttps://doaj.org/article/b7803c4943094999a6d7b123419810b7

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7190186

Europe_PMChttps://europepmc.org/articles/PMC7190186

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

CD4-Positive T-LymphocytesAnimalsMacaca mulattaSimian Acquired Immunodeficiency SyndromeGene Products, nefMembrane ProteinsRNA, ViralAntigens, CDViral LoadVirus ReplicationAmino Acid SequenceSimian immunodeficiency virusViral Regulatory and Accessory ProteinsBone Marrow Stromal Antigen 2

Keywords

CD4-Positive T-LymphocytesQH301-705.5Bone Marrow Stromal Antigen 2Simian Acquired Immunodeficiency SyndromeMembrane ProteinsRC581-607Viral LoadVirus ReplicationMacaca mulattaGene Products, nefAntigens, CDAnimalsRNA, ViralSimian Immunodeficiency VirusViral Regulatory and Accessory ProteinsAmino Acid SequenceImmunologic diseases. AllergyBiology (General)Research Article

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Residues T48 and A49 in HIV-1 NL4-3 Nef are responsible for the counteraction of autophagy initiation, which prevents the ubiquitin-dependent degradation of Gag through autophagosomes

10.6084/m9.figshare.16901011.v1figshare

10.6084/m9.figshare.16901011figshare