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Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis

PLoS Pathogens(2020)10.1371/journal.ppat.1008973Source: DataRank Database

Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis is a research paper published in PLoS Pathogens (2020). On theSindex it has a DataRank of 0. It has been cited 18 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access18 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.48)OA: goldTopics (35)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Alexandra Popa ORCID,Csilla Viczenczová,Lindsay Kosack ORCID,Kristaps Klavins ORCID,Benedikt Agerer ORCID

Live enrichment

PubMed:33045014 PMC:PMC7580883 OpenAlex:https://openalex.org/W3092549947

European Research Council

Grant: 677006

Austrian Science Fund

Grant: FWF1212

Österreichischen Akademie der Wissenschaften

Grant: DOC

FWCI

0.48

Citation Percentile

0.5%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008973&type=printable

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008973&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1008973

journalhttps://doi.org/10.1371/journal.ppat.1008973

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33045014

Fields of Study

Tryptophan and brain disordersStress Responses and CortisolImmune Cell Function and Interaction

MeSH Terms

AnimalsAntiviral AgentsFemaleHepatitis VirusesHepatitis, Viral, AnimalHumansImmunity, InnateInflammationKynurenineMaleMice, Inbred C57BLTryptophanTryptophan OxygenaseMice, KnockoutHepatocytesSTAT1 Transcription FactorInterferon Regulatory Factor-7MiceReceptor, Interferon alpha-beta

Keywords

KynurenineBiologyImmune systemKynurenine pathwayHepatocyteMetaboliteInterferonInflammationCell biologyTryptophanImmunologyBiochemistryIn vitro

Sustainable Development Goals

SDG 0: Good health and well-being