🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART

PLoS Pathogens(2021)10.1371/journal.ppat.1009214Source: DataRank Database

Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART is a research paper published in PLoS Pathogens (2021). On theSindex it has a DataRank of 1.4. It has been cited 52 times, with 36 citing works in its 1-hop citation network.

N/A

1.4DataRank · unranked

Scored on demand from live citation data

Open Access52 citations · 36 citing works in its network

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (21 grants)Impact (FWCI 4.38)OA: goldTopics (78)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 42%Citation Network 58%

Base Score Contribution

0.596

From this paper's citation signal

Citation Network Contribution

0.812

From 27 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 36 citers.

Protracted yet Coordinated Differentiation of Long-Lived SARS-CoV-2-Specific CD8+ T Cells during Convalescence
The Journal of Immunology202120 citations33 referencesContributes 0.092
Interleukin 6 Blockade With Tocilizumab Diminishes Indices of Inflammation That Are Linked to Mortality in Treated Human Immunodeficiency Virus Infection
Clinical Infectious Diseases202325 citations39 referencesContributes 0.084
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status
eLife202191 citations55 referencesContributes 0.082
T-Cell Expression of Angiotensin-Converting Enzyme 2 and Binding of Severe Acute Respiratory Coronavirus 2
The Journal of Infectious Diseases202122 citations40 referencesContributes 0.078
Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence
bioRxiv (Cold Spring Harbor Laboratory)20216 citations36 referencesContributes 0.054

Authors (24)

Mark Fitch ORCID,Jori Symons ORCID,Mohamed Abdel‐Mohsen ORCID,Daniel B. Reeves ORCID,Rebecca Hoh ORCID

Live enrichment

PubMed:33465157 PMC:PMC7846027 OpenAlex:https://openalex.org/W3123558466

National Institute of Allergy and Infectious Diseases

Grant: R01AI116368

National Institute of Allergy and Infectious Diseases

Grant: R01DK108349

National Institute of Allergy and Infectious Diseases

Grant: R01AI132128

National Institute of Allergy and Infectious Diseases

Grant: R01DK120387

amfAR, The Foundation for AIDS Research

Grant: 109301-59-RGRL

National Institute of Allergy and Infectious Diseases

Grant: UM1AI126611-01

Bill and Melinda Gates Foundation

Grant: OPP1115400

UCSF Medical Scientist Training Program

Grant: T32GM007618

Center for AIDS Research,

Grant: P30 AI027757

NIAID NIH HHS

Grant: K24 AI145806

NIAID NIH HHS

Grant: UM1 AI126611

NIAID NIH HHS

Grant: K25 AI155224

NIAID NIH HHS

Grant: P30 AI027763

National Institutes of Health

Grant: 5R01DK108349-05

Investigating Mechanisms of HIV Persistence in the Gut

National Institutes of Health

Grant: 5R01AI116368-05

Timing of ART and homeostasis of the persistent HIV reservoir in the adult

National Institutes of Health

Grant: 5R01AI132128-04

Understanding HIV latency reversal and clearance of infected cells in vivo

National Institutes of Health

Grant: 5R01DK120387-02

Novel single genome approaches to determine the mechanisms of HIV latent infection in blood, gut, and lymph nodes

National Institutes of Health

Grant: 5T32GM007618-27

MEDICAL SCIENTIIST TRAINING PROGRAM

National Institutes of Health

Grant: 3P30AI027757-36S1

University of Washington/Fred Hutch Center for AIDS Research

National Institutes of Health

Grant: 5UM1AI126611-05

Delaney AIDS Research Enterprise to Cure HIV

National Institutes of Health

Grant: 5K24AI145806-03

Persistent Functional Immune Defects in Treated HIV Infection

FWCI

4.38

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009214&type=printable

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009214&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1009214

journalhttps://doi.org/10.1371/journal.ppat.1009214

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33465157

Fields of Study

HIV Research and TreatmentImmune Cell Function and InteractionHIV/AIDS drug development and treatment0301 basic medicine03 medical and health sciences0303 health sciencesAdultAnti-Retroviral AgentsCD4-Positive T-LymphocytesCase-Control StudiesCell DifferentiationDNA, ViralHIV InfectionsHIV-1HumansMaleMiddle AgedViral LoadVirus Replication

MeSH Terms

AdultCell DifferentiationDNA, ViralHumansMaleMiddle AgedVirus ReplicationCD4-Positive T-LymphocytesHIV-1HIV InfectionsCase-Control StudiesViral LoadAnti-Retroviral Agents

Keywords

BiologyEffectorCellPersistence (discontinuity)ImmunologyLentivirusProvirusHuman immunodeficiency virus (HIV)Cell biologyMolecular biologyGeneticsViral diseaseGeneGenomeAdultCD4-Positive T-LymphocytesMale571QH301-705.5610HIV InfectionsVirus ReplicationMicrobiologyClinical ResearchVirology616HumansViralBiology (General)Biomedical and Clinical SciencesCell DifferentiationDNAMedical microbiologyRC581-607Middle AgedViral LoadInfectious DiseasesAnti-Retroviral AgentsCase-Control StudiesDNA, ViralHIV-1HIV/AIDSSexually Transmitted InfectionsImmunologic diseases. AllergyInfectionResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Related Papers (3)

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption

N/A

1.2DataRank · unranked

Cell Reports(2022)

co-cited

10.1016/j.celrep.2022.110739

Persistent HIV-1 Viremia on Antiretroviral Therapy: Measurement and Mechanisms

N/A

1.8DataRank · unranked

Frontiers in Microbiology(2019)

co-cited

10.3389/fmicb.2019.02383

A Phase 1/2 Randomized, Placebo-Controlled Trial of Romidespin in Persons With HIV-1 on Suppressive Antiretroviral Therapy

N/A

1.5DataRank · unranked

The Journal of Infectious Diseases(2020)

co-cited

10.1093/infdis/jiaa777