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ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis

PLoS Pathogens(2021)10.1371/journal.ppat.1009285Source: DataRank Database

ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis is a research paper published in PLoS Pathogens (2021). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.40)OA: goldTopics (81)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Douglas R. Wilcox ORCID,Yuchen Yang ORCID,Grace K. Coleman ORCID,Melissa A. Brown ORCID,Richard Longnecker ORCID

Live enrichment

PubMed:33524073 PMC:PMC7877773 OpenAlex:https://openalex.org/W3128835134

National Institute of Neurological Disorders and Stroke

Grant: R01NS110631

National Institute of Allergy and Infectious Diseases

Grant: F30AI150049

National Institutes of Health

Grant: T32GM008152

National Institutes of Health

Grant: 5T32GM008152-28

Medical Scientist Training Program

National Institutes of Health

Grant: 5R01NS110631-03

Role of Host Cell Factors in Newborn Herpes Simplex Virus (HSV) Encephalitis

National Institutes of Health

Grant: 5F30AI150049-04

An Age-Dependent Role of the Inflammasome in the Pathogenesis of HSV Encephalitis

FWCI

1.40

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009285&type=printable

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009285&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1009285

journalhttps://doi.org/10.1371/journal.ppat.1009285

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33524073

Fields of Study

Inflammasome and immune disordersHerpesvirus Infections and Treatmentsinterferon and immune responses0301 basic medicine03 medical and health sciencesAnimalsBrainCARD Signaling Adaptor ProteinsCells, CulturedChemokines, CCChlorocebus aethiopsDisease Models, AnimalEncephalitis, Herpes SimplexFemaleInflammasomesInflammation MediatorsInterleukin-1betaMacrophagesMaleMiceMice, Inbred C57BLMicrogliaVero Cells

MeSH Terms

AnimalsBrainCells, CulturedChlorocebus aethiopsDisease Models, AnimalFemaleMacrophagesMaleMice, Inbred C57BLVero CellsMicrogliaInflammation MediatorsChemokines, CCEncephalitis, Herpes SimplexMiceCARD Signaling Adaptor ProteinsInterleukin-1betaInflammasomes

Keywords

InflammasomeImmunologyNeuroinflammationChemokineInnate immune systemPathogenesisEncephalitisBiologyMicrogliaViral encephalitisAIM2Herpes simplex virusInflammationViral replicationNeurotropic virusImmune systemVirologyVirusMaleQH301-705.5InflammasomesInterleukin-1betaMiceChlorocebus aethiopsAnimalsBiology (General)Vero CellsCells, CulturedMacrophagesBrainRC581-607CARD Signaling Adaptor ProteinsMice, Inbred C57BLDisease Models, AnimalChemokines, CCFemaleEncephalitis, Herpes SimplexImmunologic diseases. AllergyInflammation MediatorsResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being