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Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells

PLoS Pathogens(2021)10.1371/journal.ppat.1009311Source: DataRank Database

Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells is a research paper published in PLoS Pathogens (2021). On theSindex it has a DataRank of 0. It has been cited 32 times.

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Open Access32 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: goldTopics (55)IDs (PubMed, PMC)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Allan Radaic ORCID,Erin Malone ORCID,Pachiyappan Kamarajan ORCID,Nai‐Yuan N. Chang ORCID,Christian Tafolla

Live enrichment

PubMed:34255809 PMC:PMC8301614

National Institutes of Health

Grant: R01 DE025225

National Institutes of Health

Grant: F30 DE027598

National Institutes of Health

Grant: T32DE007306

National Institutes of Health

Grant: 5T32DE007306-18

Comprehensive Oral Health Training Program

National Institutes of Health

Grant: 5R01DE025225-04

Oral Treponema Surface Proteins: Host Cell Interactions

National Institutes of Health

Grant: 5F30DE027598-02

Characterization of Treponema Denticola-Mediated Interactions With Periodontal Ligament Cells Leading to Persistent Host Cell/Tissue Destruction

goldLicense: cc-by

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009311&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1009311

repositoryhttps://escholarship.org/uc/item/1dx785v1

repositoryhttps://doaj.org/article/e3664d62e71548218d04a5e5a539a628

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8301614

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Cells, CulturedPeriodontal LigamentHumansTreponema denticolaTreponemal InfectionsPeriodontal DiseasesPeptide HydrolasesMatrix MetalloproteinasesBacterial ProteinsVirulence FactorsUp-RegulationSp1 Transcription FactorToll-Like Receptor 2Myeloid Differentiation Factor 88

Keywords

QH301-705.5Periodontal LigamentSp1 Transcription FactorVirulence Factors1.1 Normal biological development and functioningCellsImmunology610MicrobiologyOral and gastrointestinalBacterial ProteinsClinical ResearchVirology617Genetics2.1 Biological and endogenous factorsHumansDental/Oral and Craniofacial DiseaseBiology (General)Cells, CulturedPeriodontal DiseasesCulturedBiomedical and Clinical SciencesTreponemal InfectionsMedical microbiologyRC581-607Matrix MetalloproteinasesToll-Like Receptor 2Up-RegulationInfectious DiseasesDentistryMyeloid Differentiation Factor 88MicrobiomeImmunologic diseases. AllergyInfectionTreponema denticolaResearch ArticlePeptide Hydrolases

Sustainable Development Goals

SDG 3: 3. Good health