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Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration

PLoS Pathogens(2021)10.1371/journal.ppat.1009471Source: DataRank Database

Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration is a research paper published in PLoS Pathogens (2021). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (5 grants)OA: goldTopics (42)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Immanuel Grimm,Dagmar Stöhr,Chiara Antonini ORCID,Peter Lischka,Christian Sinzger ORCID

Live enrichment

PubMed:33780515 PMC:PMC8031885

Wilhelm Sander-Stiftung

Grant: 2013.002.2

Wilhelm Sander-Stiftung

Grant: 2019.029.1

NIGMS NIH HHS

Grant: P20 GM103546

National Institutes of Health

Grant: 5P20GM103546-09

Biomolecular Structure and Dynamics

International Graduate School in Molecular Medicine

goldLicense: cc-by

publisherhttps://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009471&type=printable

publisherhttps://dx.plos.org/10.1371/journal.ppat.1009471

repositoryhttps://doaj.org/article/8e05b5ed7837460fa1831522177f2ed4

repositoryhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-37743-3

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8031885

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

FibroblastsHumansCytomegalovirusCytomegalovirus InfectionsReceptor, Platelet-Derived Growth Factor alphaMutagenesis, Site-DirectedImmunoglobulin Fc FragmentsHEK293 CellsBecaplermin

Keywords

Receptor, Platelet-Derived Growth Factor alphaQH301-705.5ImmunoblottingAlaninBecaplerminCytomegalovirusFibroblastenwachstumsfaktorImmunoblotHumansEnzyme-linked immunoassaysBiology (General)info:eu-repo/classification/ddc/610info:eu-repo/classification/ddc/570AlanineEndothelial CellsNeural InhibitionGrowth factorRC581-607FibroblastsImmunoglobulin Fc FragmentsSignal inhibitionHEK293 CellsCytomegalovirus InfectionsMutagenesis, Site-DirectedIntercellular Signaling Peptides and ProteinsFibroblastImmunologic diseases. AllergyGrowth factorsSignal TransductionResearch Article

Sustainable Development Goals

SDG 3: 3. Good health

Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration

FAIR Checklist

Authors (7)

Funding (5 grants)

Open Access

Topics

Annotations (Europe PMC)