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S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies

PLoS Pathogens(2021)10.1371/journal.ppat.1009726Source: DataRank Database

S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies is a research paper published in PLoS Pathogens (2021). On theSindex it has a DataRank of 0. It has been cited 48 times.

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Open Access48 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 4.68)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

María José Lista ORCID,Mattia Ficarelli ORCID,Chad M. Swanson ORCID,Stuart J. D. Neil ORCID,Dorota Kmieć ORCID

Live enrichment

PubMed:34695163 PMC:PMC8568172 OpenAlex:https://openalex.org/W3210824266

Deutsche Forschungsgemeinschaft

Grant: KM 5/1-1

Wellcome Trust

Grant: WT098049AIA

Medical Research Foundation

Grant: MR/S000844/1

Regulation of HIV-1 and Ebola virus replication by CpG dinucleotides, ZAP and TRIM25

Medical Research Council

Grant: MR/R50225X/1

Kings College London and DRI NPIF Studentships 2017

King’s College London

Grant: MRC Doctoral Training Partnership in Biomedical Sciences

Medical Research Council

Grant: 1939180

Medical Research Council

Grant: MC_PC_15068

Wellcome Trust

Grant: unidentified

unidentified

Wellcome Trust

Grant: 098049

The molecular and cellular basis for the function of the HIV-1 Vpu protein in the targeting of host antiviral and immuno-modulatory factors.

Wellcome Trust

European & Developing Countries Clinical Trials Partnership (EDCTP)

FWCI

4.68

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.ppat.1009726

publisherhttps://doi.org/10.1371/journal.ppat.1009726

publisherhttps://dx.plos.org/10.1371/journal.ppat.1009726

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34695163

repositoryhttps://kclpure.kcl.ac.uk/portal/en/publications/9489c9c5-5c28-49f0-a9b2-c1ffe2555848

Fields of Study

Viral Infections and Immunology Researchinterferon and immune responsesRNA regulation and disease0301 basic medicine03 medical and health sciences

MeSH Terms

RNA-Binding MotifsSARS-CoV-2HeLa CellsHumansRNA VirusesRNA, ViralTransfectionVirus ReplicationHIV-1RNA-Binding ProteinsCpG IslandsPrenylationHEK293 CellsHela Cells

Keywords

BiologyViral replicationCell biologySubcellular localizationRNAAntiviral proteinBiochemistryVirologyVirusGene570QH301-705.5ZAPSARS CoV-2TransfectionVirus Replication616HumansRNA VirusesBiology (General)PrenylationSARS-CoV-2HIVRNA-Binding ProteinsCpG dinucleotideRC581-607antiviral immunityHEK293 CellsHIV-1RNA-Binding MotifsRNA, ViralCpG IslandsImmunologic diseases. AllergyResearch ArticleHeLa Cells

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being