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Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine

PLoS Pathogens(2025)10.1371/journal.ppat.1012859Source: DataRank Database

Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine is a research paper published in PLoS Pathogens (2025). On theSindex it has a DataRank of 0. It has been cited 16 times.

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Open Access16 citations

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bioproject gen uniprot pdb

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: goldTopics (27)IDs (PubMed, PMC)Annotations (4)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Elizabeth B. Sobolik ORCID,Nicholas May ORCID,Sainan Wang ORCID,Atef Fayed,Dariia Vyshenska

Live enrichment

PubMed:39804924 PMC:PMC11759387

National Institute of Allergy and Infectious Diseases

Grant: AI171403

NIAID NIH HHS

Grant: U19 AI171403

NCI NIH HHS

Grant: P30 CA013330

National Institutes of Health

Grant: 3P30CA013330-39S3

Core Support for Cancer Center

National Institutes of Health

Grant: 1U19AI171403-01

Antiviral Countermeasures Development Center (AC/DC)

European Commission

Grant: 101060066

Centre for Digitalisation of Biology Towards the Next-Generation of Biosustainable Products

goldLicense: cc-by

publisherhttps://doi.org/10.1371/journal.ppat.1012859

publisherhttps://dx.plos.org/10.1371/journal.ppat.1012859

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11759387/pdf/ppat.1012859.pdf

repositoryhttps://doaj.org/article/586bbdc6c625466eb02caac06a785bb4

Europe_PMChttps://europepmc.org/articles/PMC11759387

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsHumansMiceChikungunya virusViral Nonstructural ProteinsAntiviral AgentsDrug Resistance, ViralVirus ReplicationMutationChikungunya Fever

Keywords

QH301-705.5RC581-607Viral Nonstructural ProteinsVirus ReplicationAntiviral AgentsMiceMutationDrug Resistance, ViralAnimalsHumansChikungunya FeverImmunologic diseases. AllergyBiology (General)Chikungunya virusResearch Article

Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine

FAIR Checklist

Authors (13)

Funding (6 grants)

Open Access

Topics

Annotations (Europe PMC)