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Loss of hepatic autophagy induces α‐cell proliferation through impaired glutamine‐dependent gluconeogenesis

Physiological Reports(2025)10.14814/phy2.70381Source: DataRank Database

Loss of hepatic autophagy induces α‐cell proliferation through impaired glutamine‐dependent gluconeogenesis is a research paper published in Physiological Reports (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.10)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Joseph L. Wilkerson ORCID,Daniela Ramos ORCID,Hayden K. Low ORCID,Faith M. Bowman ORCID,Kimberley Evason ORCID

Live enrichment

PubMed:40420631 PMC:PMC12106947 OpenAlex:https://openalex.org/W4410789798

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: 5T32DK091317

NHLBI NIH HHS

Grant: R01 HL170575

National Institutes of Health

Grant: 3T32DK091317-07S1

Interdisciplinary Training Program in Metabolism

National Institutes of Health

Grant: 1ZIADK013039-04

Molecular modeling of soluble proteins

FWCI

1.10

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.14814/phy2.70381

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.14814/phy2.70381

publisherhttps://physoc.onlinelibrary.wiley.com/doi/pdf/10.14814/phy2.70381

journalhttps://doi.org/10.14814/phy2.70381

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40420631

Fields of Study

Pancreatic function and diabetesAutophagy in Disease and TherapyDiet, Metabolism, and Disease

MeSH Terms

Autophagy-Related ProteinsAnimalsAutophagyGlucagonGluconeogenesisGlutamineLiverMaleMice, Inbred C57BLMice, KnockoutCell ProliferationGlucagon-Secreting CellsMice

Keywords

AutophagyGluconeogenesisInternal medicineGlutamineEndocrinologyGlucagonBiologyInsulin resistanceGlucose homeostasisInsulinMetabolismAmino acidBiochemistryMedicineGlucoseLiver MetabolismHyperglucagonemiaAlpha CellMice, KnockoutMalePhysiologyAutophagy-Related ProteinsMice, Inbred C57BLMiceLiverGlucagon-Secreting CellsQP1-981AnimalsOriginal ArticleCell Proliferation

Sustainable Development Goals

SDG 0: Good health and well-being