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G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

Expert Opinion on Drug Discovery(2007)10.1517/17460441.2.12.1591Source: DataRank Database

G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery is a research paper published in Expert Opinion on Drug Discovery (2007). On theSindex it has a DataRank of 1.5. It has been cited 23 times, with 20 citing works in its 1-hop citation network.

N/A

1.5DataRank · unranked

Scored on demand from live citation data

23 citations · 20 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Impact (FWCI 0.50)OA: closedTopics (20)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 33%Citation Network 67%

Base Score Contribution

0.477

From this paper's citation signal

Citation Network Contribution

0.974

From 18 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 20 citers.

Label-Free Biosensor Assays in GPCR Screening
Methods in molecular biology201540 citations27 referencesContributes 0.138
History of the G Protein–Coupled Receptor (GPCR) Assays From Traditional to a State-of-the-Art Biosensor Assay
Journal of Pharmacological Sciences201460 citations30 referencesContributes 0.137
Retracted: GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF‐κB signaling pathway in colorectal cancer cells
Cancer Medicine201850 citations33 referencesContributes 0.119
Gα12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction
Oncotarget201543 citations45 referencesContributes 0.084
Gα12 regulates osteoclastogenesis by modulating NFATc1 expression
Journal of Cellular and Molecular Medicine201717 citations37 referencesContributes 0.078

Authors (1)

Sandra Siehler

Live enrichment

PubMed:23488903 OpenAlex:https://openalex.org/W2096229924

FWCI

0.50

Citation Percentile

0.6%

Citation Trend

2013

2014

2015

2016

2017

2018

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2021

2022

2025

closed

publisherhttp://www.tandfonline.com/doi/pdf/10.1517/17460441.2.12.1591

journalhttps://doi.org/10.1517/17460441.2.12.1591

repositoryhttps://pubmed.ncbi.nlm.nih.gov/23488903

Fields of Study

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase SignalingNeuropeptides and Animal Physiology

Keywords

G protein-coupled receptorHeterotrimeric G proteinRHOAG proteinSignal transductionGq alpha subunitRhodopsin-like receptorsDrug discoveryCell biologyReceptorContext (archaeology)BiologyGTPaseChemistryBiochemistryAgonistMetabotropic receptor

Sustainable Development Goals

SDG 0: Good health and well-being

G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (1)

Impact

Open Access

Topics