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DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability

The EMBO Journal(2021)10.15252/embj.2020104543Source: DataRank Database

DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability is a research paper published in The EMBO Journal (2021). On theSindex it has a DataRank of 1.1. It has been cited 28 times, with 26 citing works in its 1-hop citation network.

N/A

1.1DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access28 citations · 26 citing works in its network

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Linked data & code

gen doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE178927

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 1.55)OA: hybridTopics (93)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 46%Citation Network 54%

Base Score Contribution

0.505

From this paper's citation signal

Citation Network Contribution

0.585

From 22 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 26 citers.

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Nucleic Acids Research20246 citations44 referencesContributes 0.044
Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL
Cell Reports202329 citations79 referencesContributes 0.043
SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway
EMBO Reports202216 citations69 referencesContributes 0.041

Authors (20)

Sana Ahmed‐Seghir,Junya Tomida ORCID,Emmanuelle Despras ORCID,Caroline Pouvelle,Andrey A. Yurchenko ORCID

Live enrichment

PubMed:34533226 PMC:PMC8561639 OpenAlex:https://openalex.org/W3199784631

Fondation ARC pour la Recherche sur le Cancer

Grant: ARCPGA12019120001055_1578

Institut National Du Cancer

Grant: INCa‐DGOS‐Inserm 12551

Institut National Du Cancer

Grant: PLBIO16‐011

Agence Nationale de la Recherche

Grant: ANR‐14‐CE10‐0008‐01

Agence Nationale de la Recherche

Grant: ANR‐18‐IDEX‐0001

HHS|National Institutes of Health

Grant: CA193124

U.S. Department of Defense

Grant: W81XWH‐17‐10239

NCI NIH HHS

Grant: P01 CA193124

French National Research Agency (ANR)

Grant: ANR-14-CE10-0008

Specialized Polymerase involved in Unchallenged Replication: Requisite for duplication of heterochromatin regions during cellular differentiation and consequence on spontaneous mutagenesis

Institut National du Cancer

Grant: INCa-DGOS-INSERM-12551

SOCRATE 2.0: Stratified oncology cell DNA repair and tumor elimination 2.0

French National Research Agency (ANR)

Grant: ANR-18-IDEX-0001

National Institutes of Health

Grant: 5P01CA193124-06

Processing and Repair of DNA Crosslinks

Institut National du Cancer

Grant: unidentified

unidentified

Fondation pour la Recherche Médicale

Ministère de l'Education Nationale, de l'Enseignement Supérieur et de la Recherche

ligue nationale contre le cancer

FWCI

1.55

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://link.springer.com/content/pdf/10.15252/embj.2020104543.pdf

publisherhttps://link.springer.com/content/pdf/10.15252/embj.2020104543.pdf

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.15252/embj.2020104543

publisherhttps://link.springer.com/article/10.15252/embj.2020104543/fulltext.html

publisherhttps://www.embopress.org/doi/pdf/10.15252/embj.2020104543

Fields of Study

DNA Repair MechanismsChromosomal and Genetic VariationsCRISPR and Genetic Engineering0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsCell LineCell Line, TransformedCell ProliferationChromobox Protein Homolog 5Chromosomal InstabilityDNADNA Breaks, Double-StrandedDNA ReplicationDNA-Binding ProteinsDNA-Directed DNA PolymeraseEmbryo, MammalianEmbryonic Stem CellsEpigenesis, GeneticFibroblastsGene Expression Regulation, DevelopmentalHeLa CellsHeterochromatinHumansMiceMice, Inbred C57BLMice, TransgenicNIH 3T3 CellsSignal Transduction

MeSH Terms

Chromobox Protein Homolog 5AnimalsCell LineCell Line, TransformedDNADNA-Directed DNA PolymeraseDNA ReplicationDNA-Binding ProteinsEmbryo, MammalianFibroblastsHeLa CellsHeterochromatinHumansMice, Inbred C57BLMice, TransgenicSignal TransductionGene Expression Regulation, DevelopmentalNIH 3T3 CellsChromosomal InstabilityEpigenesis, GeneticCell ProliferationMiceEmbryonic Stem CellsDNA Breaks, Double-StrandedHela Cells

Keywords

BiologyHeterochromatinDNA replicationGenome instabilityGeneticsDNA polymeraseGenomePolymeraseDNAMolecular biologyGeneDNA damageChromatinReplication TimingRev3lTls PolymeraseDNA-Directed DNA PolymeraseCell LineEpigenesis, GeneticMiceTranscription & Genomics[SDV.CAN] Life Sciences [q-bio]/CancerChromosomal InstabilityAnimalsHumansDNA Breaks, Double-StrandedRecombination & RepairEmbryonic Stem CellsCell Line, TransformedCell ProliferationTLS polymerase Subject Categories ChromatinGene Expression Regulation, DevelopmentalArticlesFibroblastsEmbryo, MammalianDNA-Binding ProteinsChromobox Protein Homolog 5HeLa Cells

Sustainable Development Goals

SDG 0: Life in Land