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Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms

The EMBO Journal(2022)10.15252/embj.2022111065Source: DataRank Database

Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms is a research paper published in The EMBO Journal (2022). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Enrichment:Funding (18 grants)OA: hybridTopics (22)IDs (PubMed, PMC)Annotations (2)

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Authors (9)

James R. Thompson,Sepehr Dehghani‐Ghahnaviyeh ORCID,Shashank Pant ORCID,Phuoc Xuan Dang ORCID,Jarrod B. French ORCID

Live enrichment

PubMed:36484366 PMC:PMC9890230

eXtreme Science and Engineering Discovery Environment

Grant: MCA06N060

HHS ¦ NIH ¦ National Institute of General Medical Sciences

Grant: P41‐GM104601

HHS ¦ NIH ¦ National Institute of General Medical Sciences

Grant: R01‐GM123455

HHS ¦ NIH ¦ National Institute of General Medical Sciences

Grant: R35GM124898

HHS ¦ NIH ¦ National Institute on Aging

Grant: 1R21‐AG069180‐01A1

NIGMS NIH HHS

Grant: R24 GM145965

NIA NIH HHS

Grant: 1R21-AG069180-01A1

NIGMS NIH HHS

Grant: P41 GM104601

NIGMS NIH HHS

Grant: P41-GM104601

NIGMS NIH HHS

Grant: R01 GM123455

NIA NIH HHS

Grant: R21 AG069180

NIGMS NIH HHS

Grant: R01-GM123455

National Institutes of Health

Grant: 5P41GM104601-30

Center for Macromolecular Modeling and Bioinformatics

National Institutes of Health

Grant: 1R21AG069180-01A1

ABCA7 dysfunction in Alzheimer's disease pathogenesis

National Institutes of Health

Grant: 5R01GM123455-05

Toolkit for High-Resolution Structure and Dynamics of Functional Lipids

National Institutes of Health

Grant: 7R35GM124898-04

Mechanisms that govern assembly and function of higher order protein structures of purine metabolic enzymes

Hormel Foundation

Cure Alzheimer's Fund

hybridLicense: cc-by-nc-nd

publisherhttps://link.springer.com/content/pdf/10.15252/embj.2022111065.pdf

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.15252/embj.2022111065

publisherhttps://link.springer.com/article/10.15252/embj.2022111065/fulltext.html

publisherhttps://www.embopress.org/doi/pdf/10.15252/embj.2022111065

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9890230

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansPhospholipidsATP-Binding Cassette TransportersCryoelectron MicroscopyBiological TransportInterferon Regulatory FactorsMolecular Dynamics Simulation

Keywords

Alzheimer's diseaseFlippaseCryo-emAbca7ExporterCryoelectron MicroscopyInterferon Regulatory FactorsHumansATP-Binding Cassette TransportersBiological TransportArticlesMolecular Dynamics SimulationPhospholipids