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Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway

EMBO Reports(2022)10.15252/embr.202153365Source: DataRank Database

Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway is a research paper published in EMBO Reports (2022). On theSindex it has a DataRank of 3.7. It has been cited 178 times, with 100 citing works in its 1-hop citation network.

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3.7DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access178 citations · 100 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE185349 GSE185351

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)OA: goldTopics (26)IDs (PubMed, PMC)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 21%Citation Network 79%

Base Score Contribution

0.778

From this paper's citation signal

Citation Network Contribution

2.9

From 100 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 100 citers.

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Prunus mume derived extracellular vesicle-like particles alleviate experimental colitis via disrupting NEK7-NLRP3 interaction and inflammasome activation
Journal of Nanobiotechnology202522 citations39 referencesContributes 0.080
Stability of Blueberry Extracellular Vesicles and Their Gene Regulation Effects in Intestinal Caco-2 Cells
Biomolecules202333 citations45 referencesContributes 0.078
Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion
Journal of Nanobiotechnology2023169 citations68 referencesContributes 0.076

Authors (17)

Zhong‐Bin Deng,Bomei Wang,Yun Teng ORCID,Anil Kumar ORCID,Kumaran Sundaram

Live enrichment

PubMed:34994476 PMC:PMC8892346

NIGMS NIH HHS

Grant: P20 GM113226

NIGMS NIH HHS

Grant: P20 GM125504

HHS|NIH|National Institute of Environmental Health Sciences

Grant: P30ES030283

NIAAA NIH HHS

Grant: R01 AA028436

NIDDK NIH HHS

Grant: R01 DK115406

HHS|National Institutes of Health

Grant: R01AA023190

HHS|NIH|National Institute on Alcohol Abuse and Alcoholism

Grant: P50AA024337

NCCIH NIH HHS

Grant: R01 AT008617

NIGMS NIH HHS

Grant: P20 GM103436

NIAAA NIH HHS

Grant: R01 AA028435

NIAAA NIH HHS

Grant: R21 AA025724

BLRD VA

Grant: IK6 BX004199

NIDDK NIH HHS

Grant: R01 DK130294

NIAID NIH HHS

Grant: R21 AI159194

National Institutes of Health

Grant: 5IK6BX004199-04

BLR&D Research Career Scientist Award application

National Institutes of Health

Grant: 1R01AA023190-01A1

Mechanisms of Probiotics in Alcoholic Liver Disease

National Institutes of Health

Grant: 2P20GM103436-19

IDeA Networks of Biomedical Research Excellence in Kentucky

National Institutes of Health

Grant: 5R01DK115406-02

CSN8 regulation of S1P-enriched extracellular vesicles to modulate NAFLD by gut-liver axis

National Institutes of Health

Grant: 3P20GM125504-06S1

Functional Microbiomics, Inflammation and Pathogenicity

National Institutes of Health

Grant: 1R03HS013039-01

Violence &SCI: Understanding the Rehabilitation Context

National Institutes of Health

Grant: 5R01AA028435-05

Role of exosomes in the coordinated migration of neural crest cells and placodes and ethanol-induced teratogenesis

National Institutes of Health

Grant: 5P20GM113226-07

Hepatobiology and Toxicology COBRE

National Institutes of Health

Grant: 3P30ES030283-05S1

University of Louisville Center for Integrative Environmental Health Sciences

National Institutes of Health

Grant: 1P50AA024337-01

The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ Injury

National Institutes of Health

Grant: 2R01AT008617-06A1

Mechanisms underlying edible exosome-like nanoparticles for prevention of brain inflammation

goldLicense: Springer TDM

https://doi.org/10.15252/embr.202153365

https://pubmed.ncbi.nlm.nih.gov/34994476

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsMice, Inbred C57BLMiceMorusPlant BarkColitisDisease Models, AnimalNanoparticlesExosomes

Keywords

InflammationAhRAnti-microbial PeptidesCop9/cops8Mulberry Bark Derived Exosome-like NanoparticlesHeat Shock Protein Family A (Hsp70) Member 8Mice, Inbred C57BLDisease Models, AnimalMicePlant BarkAnimalsNanoparticlesMorusColitisExosomes