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Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria

EMBO Molecular Medicine(2021)10.15252/emmm.202114012Source: DataRank Database

Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria is a research paper published in EMBO Molecular Medicine (2021). On theSindex it has a DataRank of 0. It has been cited 32 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access32 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.00)OA: goldTopics (61)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Raúl Montañez ORCID,Beatriz Castejón‐Vega ORCID,Jéssica Núñez‐Vasco ORCID,Débora Lendines‐Cordero,Chun Wang ORCID

Live enrichment

PubMed:34448355 OpenAlex:https://openalex.org/W3195843085

Consejería de Salud, Junta de Andalucía

Grant: PI‐0036.2014

Progeria Research Foundation

Grant: PRF 2021‐ 80

HHS | National Institutes of Health

Grant: AR068972

HHS | National Institutes of Health

Grant: AR076758

National Institutes of Health

Grant: 1R01AR076758-01

Role of gasdermin D in bone resorption

National Institutes of Health

Grant: 1R01AR068972-01A1

Role of PARP1 in the Osteoclast Lineage

FWCI

2.00

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: other-oa

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202114012

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/emmm.202114012

publisherhttps://link.springer.com/content/pdf/10.15252/emmm.202114012.pdf

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.15252/emmm.202114012

publisherhttps://link.springer.com/article/10.15252/emmm.202114012/fulltext.html

Fields of Study

Nuclear Structure and FunctionMitochondrial Function and PathologyUbiquitin and proteasome pathways0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsDisease Models, AnimalHumansLongevityProgeriaLamin Type AMiceInflammasomes

Keywords

ProgeriaInflammasomeInflammationPhenocopyCaspase 1BiologyPhenotypePyrin domainImmunologyCell biologyGeneticsMedicine (General)AgingMedical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Initiator::Caspase 1Inflamación (Patología)Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Metabolism, Inborn Errors::ProgeriaInflammasomesMedical Subject Headings::Anatomy::Cells::Connective Tissue Cells::FibroblastsLongevityEnvejecimiento610Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::LongevityNLR FamilyQH426-470Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, AnimalMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMiceR5-920ReportNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsHumansMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::Nuclear Matrix-Associated Proteins::Lamins::Lamin Type AAnimalMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::InflammationMedical Subject Headings::Diseases::Animal Diseases::Disease Models, AnimalMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::MiceLamin Type APyrin Domain-Containing 3 ProteinNLRP3 inflammasomeMedical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::InflammasomesMedical Subject Headings::Organisms::Eukaryota::AnimalsDisease Models, AnimalMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::PhenotypeDisease ModelsNLRP3inflammasome

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Responsible consumption and production