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Spurious regulatory connections dictate the expression‐fitness landscape of translation factors

Molecular Systems Biology(2021)10.15252/msb.202110302Source: DataRank Database

Spurious regulatory connections dictate the expression‐fitness landscape of translation factors is a research paper published in Molecular Systems Biology (2021). On theSindex it has a DataRank of 0.714. It has been cited 20 times, with 15 citing works in its 1-hop citation network.

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0.714DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access20 citations · 15 citing works in its network

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Linked data & code

gen doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE162169

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 1.04)OA: goldTopics (56)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 64%Citation Network 36%

Base Score Contribution

0.457

From this paper's citation signal

Citation Network Contribution

0.258

From 11 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 15 citers.

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Cell Systems20241 citations12 referencesContributes 0.058
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Journal of Plankton Research202226 citations71 referencesContributes 0.046
Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
bioRxiv (Cold Spring Harbor Laboratory)202418 citations67 referencesContributes 0.044
Nonlinear transcriptional responses to gradual modulation of transcription factor dosage
eLife20247 citations66 referencesContributes 0.032
Non-linear transcriptional responses to gradual modulation of transcription factor dosage
eLife20244 citations66 referencesContributes 0.024

Authors (3)

Darren J. Parker ORCID,Gene‐Wei Li ORCID,Jean‐Benoît Lalanne ORCID

Live enrichment

PubMed:33900014 PMC:PMC8073009 OpenAlex:https://openalex.org/W3158393388

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Grant: Doctoral fellowship

Howard Hughes Medical Institute

Grant: International Student Research Fellowship

HHS | National Institutes of Health

Grant: R35GM124732

HHS | National Institutes of Health

Grant: T32GM007287

Natural Sciences and Engineering Research Council of Canada

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1R35GM124732-01

Evolution and Regulation of Bacterial Proteome Composition

National Institutes of Health

Grant: 5T32GM007287-12

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCES

Howard Hughes Medical Institute

Searle Scholars Program

National Science Foundation

Richard and Susan Smith Family Foundation

Pew Charitable Trusts

Alfred P. Sloan Foundation

Howard Hughes Medical Institute

FWCI

1.04

Citation Percentile

0.7%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.15252/msb.202110302.pdf

publisherhttps://link.springer.com/content/pdf/10.15252/msb.202110302.pdf

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.15252/msb.202110302

publisherhttps://link.springer.com/article/10.15252/msb.202110302/fulltext.html

publisherhttps://www.embopress.org/doi/pdf/10.15252/msb.202110302

Fields of Study

RNA and protein synthesis mechanismsCRISPR and Genetic EngineeringGenomics and Phylogenetic Studies0301 basic medicine0303 health sciences03 medical and health sciencesBacillus subtilisBacterial ProteinsBase SequenceCRISPR-Cas SystemsGene Expression Regulation, BacterialGenome, BacterialPeptide Termination FactorsProtein BiosynthesisProteomeStress, PhysiologicalTranscription, Genetic

MeSH Terms

Bacillus subtilisBacterial ProteinsBase SequencePeptide Termination FactorsStress, PhysiologicalTranscription, GeneticProtein BiosynthesisGene Expression Regulation, BacterialGenome, BacterialProteomeCRISPR-Cas Systems

Keywords

Library scienceGene technologyOak Ridge National LaboratoryBiologyComputer sciencePhysicsTranslation FactorsMultiscale MeasurementsRegulatory EntrenchmentExpression-fitness LandscapePeptide Chain Release FactorsMedicine (General)Base SequenceProteomeTranscription, GeneticQH301-705.5ArticlesGene Expression Regulation, BacterialR5-920Bacterial Proteinsexpression‐fitness landscapeStress, PhysiologicalProtein BiosynthesisBiology (General)CRISPR-Cas SystemsGenome, BacterialBacillus subtilisPeptide Termination Factors

Sustainable Development Goals

SDG 0: Life in Land