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Engineering a “muco-trapping” ACE2-immunoglobulin hybrid with picomolar affinity as an inhaled, pan-variant immunotherapy for COVID-19

UNC Libraries(2024)10.17615/6j94-g634Source: DataRank Database

Engineering a “muco-trapping” ACE2-immunoglobulin hybrid with picomolar affinity as an inhaled, pan-variant immunotherapy for COVID-19 is a research paper published in UNC Libraries (2024). On theSindex it has a DataRank of 0.

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0DataRank · unranked

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Open Access0 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: greenTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Whitney Wolf,Lai S.K.,Axel Schaefer,Hutchins J.T,Ma A.

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4401280994

National Institutes of Health

Grant: 3UL1TR002489-02S1

North Carolina Translational and Clinical Science Institute (NC TraCS)

National Institutes of Health

Grant: 1R43AI149894-01A1

Aerosol immunotherapy for treatment of human metapneumovirus infection

National Science Foundation

Grant: 2028758

RAPID: A Lung Mucus Strategy for COVID-19 Viral Protection

National Science Foundation

Grant: 1903010

Rapid: Impact of Hurricane Florence on Drinking Water Safety in Eastern and Central North Carolina: Rapid Assessment and Recommendations for Recovery and Resilience

FWCI

0.00

Citation Percentile

0.2%

greenLicense: CC BY

repositoryhttps://doi.org/10.17615/6j94-g634

https://doi.org/10.1002/btm2.10650

https://dx.doi.org/10.17615/6j94-g634

https://pubmed.ncbi.nlm.nih.gov/39036085

http://dx.doi.org/10.1002/btm2.10650

Fields of Study

Inhalation and Respiratory Drug Delivery0301 basic medicine03 medical and health sciences

Keywords

Coronavirus disease 2019 (COVID-19)TrappingImmunotherapyAntibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakChemistryVirologyComputational biologyImmunologyMedicineBiologyImmune systemInternal medicineinhaled deliveryACE2RM1-950immunodecoyChemical engineeringCOVID‐19drug deliveryTP155-156Therapeutics. PharmacologyTP248.13-248.65BiotechnologyResearch Article

Sustainable Development Goals

SDG 3: 3. Good health