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A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell

UNC Libraries(2020)10.17615/gfrr-b738Source: DataRank Database

A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell is a research paper published in UNC Libraries (2020). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)Impact (FWCI 0.00)OA: greenTopics (43)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Christian Fuchsberger ORCID,Johanna Kuusisto ORCID,Markku Laakso ORCID,Michael Boehnke ORCID,Michael L. Stitzel ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4300212394

National Institutes of Health

Grant: 3R21DA027040-02S1

Identifying disease-related functional regulatory variants in open chromatin

Research Council of Finland

Grant: 124243

Identification of new genes for type 2 diabetes

Wellcome Trust

Grant: unidentified

unidentified

Research Council of Finland

Grant: 77299

Atherosclerosis, insulin resistance and diabetic macroangiopathy

National Institutes of Health

Grant: 1R01DK062370-01A1

Identifying Genes for Type 2 Diabetes: FUSION

National Institutes of Health

Grant: 3R01DK093757-05S1

Genetic epidemiology of rare and regulatory variants for metabolic traits

National Institutes of Health

Grant: 1Z01HG000024-09

Genetic analysis of type II diabetes in Finnish populati

National Institutes of Health

Grant: 2R01DK072193-10

Targeted Genetic Analysis of T2D and Quantitative Traits

National Institutes of Health

Grant: 5R00DK092251-05

Investigation of noncoding variation in human pancreatic islets and their develop

FWCI

0.00

Citation Percentile

0.4%

greenLicense: Elsevier Non-Commercial

repositoryhttps://doi.org/10.17615/gfrr-b738

https://doi.org/10.1016/j.ajhg.2013.12.011

http://www.cell.com/article/S0002929713005818/pdf

https://dx.doi.org/10.17615/gfrr-b738

https://pubmed.ncbi.nlm.nih.gov/24439111

Fields of Study

Pancreatic function and diabetesDiabetes and associated disordersPancreatitis Pathology and Treatment0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Locus (genetics)Beta cellBETA (programming language)Type 2 diabetesBiologyGeneticsExpression (computer science)Diabetes mellitusComputational biologyGeneEndocrinologyComputer scienceIsletMalePAX6 Transcription Factor610Polymorphism, Single NucleotideCell LineMiceInsulin-Secreting CellsMedicine and Health SciencesAnimalsHumansPaired Box Transcription FactorsGenetics(clinical)Genetic Predisposition to DiseaseEye ProteinsPromoter Regions, GeneticAllelesAdaptor Proteins, Signal TransducingAgedHomeodomain ProteinsLife SciencesMiddle AgedDiabetes Mellitus, Type 2Genetic LociGenome-Wide Association Study

Sustainable Development Goals

SDG 0: Good health and well-being