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Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

Research Square(2020)10.21203/rs.3.rs-33900/v2Source: DataRank Database

Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice is a research paper published in Research Square (2020). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (41)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (14)

Peter B. C. Lin,Taylor Pennington,Gonzalo Viana Di Prisco ORCID,Asha Jacob Jannu,Guixiang Xu

Live enrichment

PubMed:42529674 OpenAlex:https://openalex.org/W3194186836

National Institutes of Health

Grant: 7RF1AG051495-02

Central and Peripheral Roles of TREM2 in Alzheimer's Disease

National Institutes of Health

Grant: 3U54AG054345-05S1

IU/JAX/Pitt MODEL-AD: Deep Phenotyping Metabolomics Year 1

greenLicense: cc-by

repositoryhttps://www.researchsquare.com/article/rs-33900/v2.pdf?c=1601060397000

publisherhttps://www.researchsquare.com/article/rs-33900/v2

publisherhttps://www.researchsquare.com/article/rs-33900/v2.html

repositoryhttps://doi.org/10.21203/rs.3.rs-33900/v2

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsAdvanced battery technologies researchNeonatal and fetal brain pathology0301 basic medicine03 medical and health sciences

Keywords

TREM2MutationNeuroscienceBiologyCell biologyGeneticsReceptorGeneNHDSynaptic plasticityMiceAlzheimer DiseaseAnimalsReceptors, ImmunologicTranscriptomicsRC346-429Oligodendrocytes/myelinMice, KnockoutNeuronsMembrane GlycoproteinsNeuronal PlasticityRC952-954.6Trem2-Y38CMice, Inbred C57BLDisease Models, AnimalGeriatricsSynaptic lossSynapsesEarly-onset dementiaNeurology. Diseases of the nervous systemMicrogliaResearch Articlenavigationoperative efficiencyspine surgeryultrasonography

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being