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Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells

Research Square(2020)10.21203/rs.3.rs-45895/v1Source: DataRank Database

Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells is a research paper published in Research Square (2020). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: greenTopics (40)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (12)

Dong Li ORCID,Fangxu Sun ORCID,Antonio Rampoldi ORCID,Joshua T. Maxwell ORCID,Ronghu Wu ORCID

Live enrichment

PubMed:36284789 OpenAlex:https://openalex.org/W4244611365

National Institutes of Health

Grant: 5R01HL136345-03

Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes

National Institutes of Health

Grant: 5R21AA025723-02

A systematic analysis of alcohol-induced cardiotoxicity in human pluripotent stem cell-derived cardiomyocytes

National Institutes of Health

Grant: 5UL1TR002378-09

Georgia Clinical & Translational Science Alliance (Georgia CTSA)

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Grant: NC/P001076/1

Biotechnology and Biological Sciences Research Council

Grant: BBS/E/T/000PR9817

Wellcome Trust

Grant: 209558/Z/17/Z

HCRW_

Grant: RFPPB-18-1497(T)

Medical Research Council

Grant: MR/S036954/1

Medical Research Council

Grant: MR/K010468/1

greenLicense: cc-by

repositoryhttps://www.researchsquare.com/article/rs-45895/latest.pdf

publisherhttps://www.researchsquare.com/article/rs-45895/v1

publisherhttps://www.researchsquare.com/article/rs-45895/v1.html

repositoryhttps://doi.org/10.21203/rs.3.rs-45895/v1

Fields of Study

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative MedicineCardiac Ischemia and Reperfusion0303 health sciences03 medical and health sciences

Keywords

CardiotoxicityOxidative stressInduced pluripotent stem cellMelphalanHuman Induced Pluripotent Stem CellsStem cellCell biologyBiologyCancer researchChemistryPharmacologyMedicineInternal medicineEndocrinologyBiochemistryToxicityGeneChemotherapyEmbryonic stem cellProteomicsMedicine (General)ResearchInduced Pluripotent Stem CellsStem cellsQD415-436ContractilityR5-920HumansMyocytes, CardiacCells, Culturedcarotid-cavernous fistulaendoscopyendovascular treatmenttranssphenoidal surgeryvideo

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being