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Therapeutic Targeting of Histone Lysine Demethylase KDM4B Blocks the Growth of Castration-Resistant Prostate Cancer

Research Square(2021)10.21203/rs.3.rs-957516/v2Source: DataRank Database

Therapeutic Targeting of Histone Lysine Demethylase KDM4B Blocks the Growth of Castration-Resistant Prostate Cancer is a research paper published in Research Square (2021). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (38)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (19)

Yuan Chen ORCID,Yanping Liang ORCID,Zhenhua Chen ORCID,Jun Lü ORCID,Yong Hu Fang

Live enrichment

PubMed:42529674 OpenAlex:https://openalex.org/W3208411504

National Institutes of Health

Grant: 5R01CA215063-03

Targeting KDM4B, a novel alternative splicing regulator, in castration-resistant prostate cancer (CRPC)

National Institutes of Health

Grant: 3R41CA261384-01S1

Development of small molecule epigenetic therapeutics for prostate cancer

greenLicense: cc-by

repositoryhttps://www.researchsquare.com/article/rs-957516/latest.pdf

publisherhttps://www.researchsquare.com/article/rs-957516/v2

publisherhttps://www.researchsquare.com/article/rs-957516/v2.html

repositoryhttps://doi.org/10.21203/rs.3.rs-957516/v2

Fields of Study

Epigenetics and DNA MethylationProstate Cancer Treatment and ResearchHistone Deacetylase Inhibitors Research0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

DemethylaseProstate cancerHistoneCancer researchLysineProstateCastrationCancerMedicineBiologyInternal medicineChemistryBiochemistryGeneHormoneAmino acidMaleHistone DemethylasesJumonji Domain-Containing Histone DemethylasesAndrogen AntagonistsArticleMiceProstatic Neoplasms, Castration-ResistantReceptors, AndrogenCell Line, TumorHumansAnimalsCell Proliferationnavigationoperative efficiencyspine surgeryultrasonography

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being