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18 F-FPP-RGD 2 PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction–Associated Steatohepatitis

Journal of Nuclear Medicine(2025)10.2967/jnumed.125.270047Source: DataRank Database

18 F-FPP-RGD 2 PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction–Associated Steatohepatitis is a research paper published in Journal of Nuclear Medicine (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: closedTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Authors (12)

Caiyuan Zhang,Mozhdeh Sojoodi ORCID,Nicholas J. Rotile ORCID,Yu Lan ORCID,Stephen C. Barrett ORCID

Live enrichment

PubMed:40935611 PMC:PMC12582189 OpenAlex:https://openalex.org/W4414120223

NIH HHS

Grant: S10 OD032138

NHLBI NIH HHS

Grant: K25 HL148837

NIH HHS

Grant: S10 OD023503

NIH HHS

Grant: S10 OD025234

NIDDK NIH HHS

Grant: R01 DK121789

NIH HHS

Grant: S10 OD028499

FWCI

0.00

Citation Percentile

0.3%

closed

publisherhttps://syndication.highwire.org/content/doi/10.2967/jnumed.125.270047

journalhttps://doi.org/10.2967/jnumed.125.270047

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40935611

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12582189

Fields of Study

Liver Disease Diagnosis and TreatmentLiver physiology and pathologyFibroblast Growth Factor ResearchMedicineAnimalsPositron-Emission TomographyMiceDisease Models, AnimalOligopeptidesLiver CirrhosisMaleFatty LiverIntegrin alphaVbeta3HumansFluorine RadioisotopesIntegrins

MeSH Terms

AnimalsDisease Models, AnimalFatty LiverFluorine RadioisotopesHumansLiver CirrhosisMaleOligopeptidesIntegrinsIntegrin alphaVbeta3Positron-Emission TomographyMice

Keywords

SteatohepatitisSirius RedFibrosisAntagonistHepatic fibrosisHydroxyprolineIntegrinHepatic stellate cellRGDLiver fibrosisIntegrin Αvβ3Pet/mriMash

18 F-FPP-RGD 2 PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction–Associated Steatohepatitis

FAIR Checklist

Authors (12)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)