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ABCB1 limits the cytotoxic activity of TAK-243, an inhibitor of the ubiquitin-activating enzyme UBA1

Frontiers in Bioscience-Landmark(2022)10.31083/j.fbl2701005Source: DataRank Database

ABCB1 limits the cytotoxic activity of TAK-243, an inhibitor of the ubiquitin-activating enzyme UBA1 is a research paper published in Frontiers in Bioscience-Landmark (2022). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (1 grants)Impact (FWCI 0.82)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Yuqi Yang ORCID,Zi‐Ning Lei ORCID,Silpa Narayanan,Jing‐Quan Wang ORCID,Qiu‐Xu Teng

Live enrichment

PubMed:35090310 PMC:PMC10258814 OpenAlex:https://openalex.org/W4205549528

Intramural NIH HHS

Grant: ZIA BC010030

FWCI

0.82

Citation Percentile

0.7%

Citation Trend

2022

2024

2025

2026

goldLicense: cc-by

journalhttps://www.imrpress.com/journal/FBL/27/1/10.31083/j.fbl2701005/pdf

GOLDhttps://www.imrpress.com/journal/FBL/27/1/10.31083/j.fbl2701005/pdf

publisherhttps://www.imrpress.com/journal/FBL/27/1/10.31083/j.fbl2701005/pdf

publisherhttps://www.imrpress.com/journal/FBL/27/1/10.31083/j.fbl2701005

journalhttps://doi.org/10.31083/j.fbl2701005

Fields of Study

Drug Transport and Resistance MechanismsCholesterol and Lipid MetabolismPeroxisome Proliferator-Activated ReceptorsMedicineChemistryATP Binding Cassette Transporter, Subfamily BAntineoplastic AgentsCell Line, TumorDrug Resistance, NeoplasmHumansMolecular Docking SimulationPyrazolesPyrimidinesSulfidesSulfonamidesUbiquitin-Activating Enzymes

MeSH Terms

Antineoplastic AgentsHumansPyrazolesPyrimidinesSulfidesSulfonamidesATP Binding Cassette Transporter, Subfamily BDrug Resistance, NeoplasmUbiquitin-Activating EnzymesCell Line, TumorMolecular Docking Simulation

Keywords

CytotoxicityMTT assayMultiple drug resistanceChemistryMultidrug resistance-associated protein 2Western blotP-glycoproteinTransporterDocking (animal)ATP-binding cassette transporterIC50PharmacologyDrug resistanceUbiquitinCancer cellIn vitroMolecular biologyBiochemistryBiologyCancerGeneMedicineMultidrug resistanceAbcb1Ubiquitin-activating EnzymeTak-243<I>in Vitro</i> Cytotoxicity

Sustainable Development Goals

SDG 0: Good health and well-being