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Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART−/−IL2RG−/Y SCID Pigs

Frontiers in Immunology(2020)10.3389/fimmu.2020.00100Source: DataRank Database

Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART−/−IL2RG−/Y SCID Pigs is a research paper published in Frontiers in Immunology (2020). On theSindex it has a DataRank of 0. It has been cited 41 times.

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Open Access41 citations

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Enrichment:Funding (3 grants)OA: goldTopics (50)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (25)

Yunsheng Li ORCID,A Ahrens,Matti Kiupel ORCID,Kristen A. Byrne ORCID,Crystal L. Loving ORCID

Live enrichment

PubMed:32117254 PMC:PMC7017803

NIH HHS

Grant: R24 OD019813

National Institutes of Health

Grant: 3R24OD019813-04S1

Expanding the Utility of Severe Combined Immuno-Deficient (SCID) Pig Models

National Institutes of Health

goldLicense: cc-by

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2020.00100/pdf

publisherhttps://www.frontiersin.org/article/10.3389/fimmu.2020.00100/full

repositoryhttps://doaj.org/article/90e19bfaff564e6cba09fec4106130d4

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7017803

Europe_PMChttps://europepmc.org/articles/PMC7017803

Fields of Study

0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

Killer Cells, NaturalT-LymphocytesAnimalsChimeraAnimals, Genetically ModifiedSwineHumansSevere Combined ImmunodeficiencyDisease Models, AnimalDNA-Binding ProteinsAntigens, CD34Bone Marrow TransplantationTransplantation, HeterologousGene TargetingGenetic EngineeringModels, AnimalCell DifferentiationHost vs Graft ReactionGraft SurvivalInterleukin Receptor Common gamma SubunitCRISPR-Cas Systems

Keywords

SwineSCIDSevere combined immunodeficiencyhumanizationBiomedical ModelT-LymphocytesImmunologyAntigens, CD34Animals, Genetically ModifiedAnimalsHumansBone Marrow TransplantationChimeraGraft SurvivalCell DifferentiationRC581-607DNA-Binding ProteinsKiller Cells, NaturalDisease Models, AnimalHost vs Graft ReactionGene TargetingModels, AnimalImmunologic diseases. AllergyCRISPR-Cas SystemsGenetic EngineeringInterleukin Receptor Common gamma Subunit

Sustainable Development Goals

SDG 3: 3. Good health

Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART−/−IL2RG−/Y SCID Pigs

FAIR Checklist

Authors (25)

Funding (3 grants)

Open Access

Topics

Annotations (Europe PMC)