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Answered and Unanswered Questions in Early-Stage Viral Vector Transduction Biology and Innate Primary Cell Toxicity for Ex-Vivo Gene Editing

Frontiers in Immunology(2021)10.3389/fimmu.2021.660302Source: DataRank Database

Answered and Unanswered Questions in Early-Stage Viral Vector Transduction Biology and Innate Primary Cell Toxicity for Ex-Vivo Gene Editing is a research paper published in Frontiers in Immunology (2021). On theSindex it has a DataRank of 0. It has been cited 29 times.

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Open Access29 citations

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Enrichment:Funding (1 grants)Impact (FWCI 3.17)OA: goldTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Matthew H. Porteus ORCID,Amanda M. Dudek ORCID

Live enrichment

PubMed:34122418 PMC:PMC8195279 OpenAlex:https://openalex.org/W3172355085

NHLBI NIH HHS

Grant: F32 HL154667

FWCI

3.17

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.660302/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.660302/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.660302/full

journalhttps://doi.org/10.3389/fimmu.2021.660302

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34122418

Fields of Study

Virus-based gene therapy researchCRISPR and Genetic EngineeringViral Infections and Immunology Research

MeSH Terms

Gene EditingDependovirusAnimalsCapsidDNA DamageGenetic VectorsHumansImmunity, InnateGenetic TherapyGenome, ViralCapsid ProteinsMiceCRISPR-Cas Systems

Keywords

Genome editingBiologyInnate immune systemTransduction (biophysics)Progenitor cellEx vivoStem cellHaematopoiesisImmune systemImmunologyCRISPRComputational biologyCell biologyGeneGeneticsIn vivoParvovirusToxicityHematopoietic stem cellViral vectorDna Damage Response (Ddr)Hematopoietic Stem Cell (Hsc) TransplantationAav (Adeno-associated Virus)Genome-edited Cells

Sustainable Development Goals

SDG 0: Good health and well-being

Answered and Unanswered Questions in Early-Stage Viral Vector Transduction Biology and Innate Primary Cell Toxicity for Ex-Vivo Gene Editing

FAIR Checklist

Authors (2)

Funding (1 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)