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A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells

Frontiers in Immunology(2021)10.3389/fimmu.2021.679675Source: DataRank Database

A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells is a research paper published in Frontiers in Immunology (2021). On theSindex it has a DataRank of 0.591. It has been cited 12 times, with 11 citing works in its 1-hop citation network.

N/A

0.591DataRank · unranked

Scored on demand from live citation data

Open Access12 citations · 11 citing works in its network

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Linked data & code

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DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 0.59)OA: goldTopics (81)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 65%Citation Network 35%

Base Score Contribution

0.385

From this paper's citation signal

Citation Network Contribution

0.206

From 10 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 11 citers.

Human HLA-DR+CD27+ regulatory T cells show enhanced antigen-specific suppressive function
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Treg Therapy for the Induction of Immune Tolerance in Transplantation—Not Lost in Translation?
International Journal of Molecular Sciences202329 citations80 referencesContributes 0.043
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Annual Review of Medicine202316 citations73 referencesContributes 0.039
Clinical Manufacturing of Regulatory T Cell Products For Adoptive Cell Therapy and Strategies to Improve Therapeutic Efficacy
Organogenesis202322 citations120 referencesContributes 0.026
Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients
Frontiers in Immunology20254 citations83 referencesContributes 0.019

Authors (9)

Hong Zhang ORCID,Karim Lee,Horace Liang,Alexander A. Merleev ORCID,Flavio Vincenti ORCID

Live enrichment

PubMed:34220826 PMC:PMC8253048 OpenAlex:https://openalex.org/W3173900521

National Institute of Allergy and Infectious Diseases

Grant: A130726, 1U01AI110658, R01 AI 118777, U19 AI 131453, U01 AI 36779, T32 AI 74490

National Institutes of Health

Grant: NIH P30 DK063720, S10 1S10OD018040-01

NCI NIH HHS

Grant: P30 CA093373

NIH HHS

Grant: S10 OD018040

NIDDK NIH HHS

Grant: P30 DK063720

NIAID NIH HHS

Grant: R01 AI118777

NIAID NIH HHS

Grant: U01 AI110658

NIAID NIH HHS

Grant: U19 AI131453

National Institutes of Health

Grant: 5P30DK063720-03

ISLET PRODUCTION FACILITY CORE

National Institutes of Health

Grant: 5U01AI110658-04

Donor-Alloantigen-Reactive Regulatory T Cell Therapy in Liver Transplantation

National Institutes of Health

Grant: 5T32AI074490-15

Interdisciplinary Training in Transplantation Biology

National Institutes of Health

Grant: 3P30CA093373-07S2

Cancer Center Support Grant - P30

National Institutes of Health

Grant: 1S10OD018040-01

UCSF DVS CyTOF Mass Cytometer

National Institutes of Health

Grant: 5U19AI131453-02

Regulatory immune cell therapy, promotion of tolerance and underlying mechanisms in NHP renal transplantation

National Institutes of Health

Grant: 1R01AI118777-01A1

Regulation of Liver DC Function and Transplant Tolerance

FWCI

0.59

Citation Percentile

0.6%

Citation Trend

2021

2022

2023

2024

2025

goldLicense: cc-by

journalhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.679675/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.679675/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2021.679675/full

journalhttps://doi.org/10.3389/fimmu.2021.679675

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34220826

Fields of Study

T-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesImmune Cell Function and Interaction0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

B-LymphocytesCells, CulturedDendritic CellsHumansIsoantigensLymphocyte Culture Test, MixedLymphocyte ActivationPhenotypeReceptors, Antigen, T-CellBiomarkersImmunophenotypingCytokinesCell Culture TechniquesT-Cell Antigen Receptor SpecificityT-Lymphocytes, Regulatory

Keywords

CD86FOXP3CD80CD40IL-2 receptorChemokineEx vivoCell biologyAntigen-presenting cellImmunologyDendritic cellImmune systemBiologyT cellChemistryCytotoxic T cellIn vitroHumanTransplantationDendritic cellsImmune regulationregulatory T celltransplant toleranceB cellsTreg TherapyIsoantigens1.1 Normal biological development and functioningCellsT-LymphocytesCell Culture TechniquesReceptors, Antigen, T-Cell610T-Cell Antigen Receptor SpecificityLymphocyte ActivationT-Lymphocytes, RegulatoryImmunophenotypingReceptorsGeneticsImmunology and AllergyHumansLymphocyte Culture TestCells, CulturedB-LymphocytesCulturedBiomedical and Clinical Sciences5.2 Cellular and gene therapiesInflammatory and immune system600RC581-607T-CellRegulatoryMixedPhenotypeMedical MicrobiologyAntigenBiochemistry and cell biologyCytokinesImmunologic diseases. AllergyLymphocyte Culture Test, MixedBiomarkers