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Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements

Frontiers in Immunology(2022)10.3389/fimmu.2022.940095Source: DataRank Database

Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements is a research paper published in Frontiers in Immunology (2022). On theSindex it has a DataRank of 0. It has been cited 32 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access32 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 1.96)OA: goldTopics (80)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Laure Aurelian ORCID,Kimberly S. Williams ORCID,Brian Campbell ORCID,Rick B. Meeker ORCID,A. Leslie Morrow ORCID

Live enrichment

PubMed:35967446 OpenAlex:https://openalex.org/W4288715934

National Institutes of Health

Grant: 5R01AA024095-04

Gene Delivery of Neuroactive Steroids to Modulate Ethanol Reinforcement/Consumption

National Institutes of Health

Grant: 1R01NS108808-01

Neural network dysfunction in early HIV neuropathogenesis

NIAAA NIH HHS

Grant: R01 AA024095

NINDS NIH HHS

Grant: R01 NS108808

FWCI

1.96

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.3389/fimmu.2022.940095

publisherhttps://doi.org/10.3389/fimmu.2022.940095

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2022.940095/full

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35967446

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9373802

Fields of Study

Immune Response and InflammationReproductive System and PregnancyNeuroinflammation and Neurodegeneration Mechanisms0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsChemokinesCytokinesFemaleHumansImiquimodLeukocytes, MononuclearLipopolysaccharidesMacrophage ActivationMaleMiceNeurosteroidsPregnanoloneSignal TransductionToll-Like Receptor 4Toll-Like Receptor 7Toll-Like Receptors

MeSH Terms

ImiquimodNeurosteroidsAnimalsFemaleHumansLeukocytes, MononuclearLipopolysaccharidesMacrophage ActivationMalePregnanoloneSignal TransductionCytokinesChemokinesToll-Like ReceptorsToll-Like Receptor 4Toll-Like Receptor 7Mice

Keywords

AllopregnanoloneTLR4ChemokineNeuroactive steroidEndocrinologyInternal medicineTLR7InflammationCytokineReceptorToll-like receptorMonocytePharmacologyBiologyChemistryImmunologyMedicineInnate immune systemLipopolysaccharidesMaleneurosteroid (3α, 5α)-3 21-dihydroxypregnan-20-one (3α, 5α-THDOC)PregnanoloneMiceSGE-516AnimalsHumansallopregnanolone (3α, 5α-THP)ImiquimodToll-Like ReceptorsRC581-607Macrophage ActivationcytokinesToll-Like Receptor 4Toll-Like Receptor 7Leukocytes, MononuclearFemaleImmunologic diseases. AllergyChemokinesNeurosteroidsSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being