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Paneth cell dysfunction in radiation injury and radio-mitigation by human α-defensin 5

Frontiers in Immunology(2023)10.3389/fimmu.2023.1174140Source: DataRank Database

Paneth cell dysfunction in radiation injury and radio-mitigation by human α-defensin 5 is a research paper published in Frontiers in Immunology (2023). On theSindex it has a DataRank of 0.614. It has been cited 14 times, with 13 citing works in its 1-hop citation network.

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0.614DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access14 citations · 13 citing works in its network

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Linked data & code

bioproject doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

figshare10.6084/m9.figshare.19758832

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 1.62)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 66%Citation Network 34%

Base Score Contribution

0.406

From this paper's citation signal

Citation Network Contribution

0.207

From 10 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 13 citers.

Spatial Proteomics Reveals Alcohol-Induced Damages to the Crypts and Villi of the Mouse Small Intestine
Journal of Proteome Research20246 citations36 referencesContributes 0.054
Application of a derivative of human defensin 5 to treat ionizing radiation-induced enterogenic infection
Journal of Radiation Research202411 citations48 referencesContributes 0.052
Human α-Defensin 51–9 and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet
International Journal of Molecular Sciences202314 citations89 referencesContributes 0.030
Gastrointestinal mucositis: a sign of a (systemic) inflammatory response
Current Opinion in Supportive and Palliative Care20245 citations63 referencesContributes 0.028
Paneth Cells: Dispensable yet Irreplaceable for the Intestinal Stem Cell Niche
Cellular and Molecular Gastroenterology and Hepatology202419 citations154 referencesContributes 0.019

Authors (13)

Roshan G. Rao,Avtar S. Meena ORCID,Francesco Giorgianni ORCID,Sue Çhin Lee ORCID,Preeti Raju

Live enrichment

PubMed:37638013 PMC:PMC10448521 OpenAlex:https://openalex.org/W4385720379

NIDDK NIH HHS

Grant: R01 DK125047

National Institutes of Health

Grant: AA12307

NIAID NIH HHS

Grant: U01 AI172991

National Institutes of Health

Grant: AI170019

National Institutes of Health

Grant: AI01080405

NIDDK NIH HHS

Grant: R01 DK055532

NIDDK NIH HHS

Grant: R56 DK055532

National Institutes of Health

Grant: DK55532

NIAID NIH HHS

Grant: U19 AI150574

NIAAA NIH HHS

Grant: R01 AA012307

NIAID NIH HHS

Grant: U01 AI170019

National Institutes of Health

Grant: 5U01AI170019-03

Radiation-Induced Paneth Cell Dysfunction

National Institutes of Health

Grant: 5R01DK055532-20

Intestinal Mucosal Protection by epidermal Growth Factor

National Institutes of Health

Grant: 5U19AI150574-03

Intercollaborative Radiation Countermeasure (INTERACT) Consortium for Advanced Development of Medical Countermeasures to Mitigate/Treat Acute and Delayed Radiation Syndromes

National Institutes of Health

Grant: 5R01DK125047-03

Dysbiosis in Hirschsprung Associated Enterocolitis Pathogenesis

National Institutes of Health

Grant: 5R01AA012307-15

Mechanism of Endotoxin absorption in alcoholism

FWCI

1.62

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.frontiersin.org/articles/10.3389/fimmu.2023.1174140/pdf

journalhttps://doi.org/10.3389/fimmu.2023.1174140

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37638013

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10448521

repositoryhttps://doaj.org/article/2b2aefb595764eb3a340fbbf4f20d09e

Fields of Study

Gut microbiota and healthAntimicrobial Peptides and ActivitiesProbiotics and Fermented Foods0301 basic medicine03 medical and health sciences

MeSH Terms

AdultAnimalsHumansInflammationRadiation InjuriesRNA, Ribosomal, 16SCytokinesEndotoxemiaPaneth Cellsalpha-DefensinsMiceDysbiosis

Keywords

DefensinRadiation injuryPaneth cellMedicineBiologyInternal medicineMicrobiologyRadiation therapyAntimicrobialIntestineIrradiationDefensinsTight junctionMicrobiomeBarrier FunctionGi-arsAdultInflammationPaneth Cellsalpha-DefensinsImmunologyRC581-607EndotoxemiaMiceRNA, Ribosomal, 16SHumansAnimalsDysbiosisCytokinesImmunologic diseases. AllergyRadiation Injuries