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Aging induces T cells with distinct transcriptomic profiles and functions in brain-associated tissues

Frontiers in Immunology(2025)10.3389/fimmu.2025.1619196Source: DataRank Database

Aging induces T cells with distinct transcriptomic profiles and functions in brain-associated tissues is a research paper published in Frontiers in Immunology (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.38)OA: goldTopics (52)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Yuanyue Zhang ORCID,Qi Yang ORCID,Youwen Si ORCID

Live enrichment

PubMed:40534878 PMC:PMC12174455 OpenAlex:https://openalex.org/W4411042243

National Institutes of Health

Grant: R01HL155021 (QY), RF1AG078459 (QY)

NHLBI NIH HHS

Grant: R01 HL155021

NIA NIH HHS

Grant: RF1 AG078459

National Institutes of Health

Grant: 5R01HL155021-03

Function and regulation of mucosal associated invariant T cells in the lung

National Institutes of Health

Grant: 1RF1AG078459-01A1

The development and function of aging-associate innate lymphoid cells in the choroid plexus

FWCI

0.38

Citation Percentile

0.6%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1619196/pdf

publisherhttps://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1619196/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2025.1619196/full

journalhttps://doi.org/10.3389/fimmu.2025.1619196

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40534878

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsT-cell and B-cell ImmunologyAtherosclerosis and Cardiovascular Diseases

MeSH Terms

AgingAnimalsBrainChoroid PlexusHippocampusMaleMeningesMice, Inbred C57BLCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesGene Expression ProfilingMiceSingle-Cell AnalysisTranscriptome

Keywords

Choroid plexusTranscriptomeBiologyCD8Cell biologyCytotoxic T cellImmune systemFlow cytometryMicrogliaImmunologyNeuroscienceInflammationGene expressionCentral nervous systemIn vitroGeneticsGeneAgingCD4T cellCognitive functionCd153MaleCD4-Positive T-LymphocytesGene Expression ProfilingBrainRC581-607CD8-Positive T-LymphocytesHippocampusMice, Inbred C57BLMiceMeningesAnimalsImmunologic diseases. AllergySingle-Cell Analysis

Sustainable Development Goals

SDG 0: Good health and well-being