Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s

Frontiers in Neuroscience(2020)10.3389/fnins.2020.00443Source: DataRank Database

LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s is a research paper published in Frontiers in Neuroscience (2020). On theSindex it has a DataRank of 2.1. It has been cited 86 times, with 75 citing works in its 1-hop citation network.

N/A

2.1DataRank · unranked

Scored on demand from live citation data

Open Access86 citations · 75 citing works in its network

Download PDF

Cite:

Linked data & code

doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)OA: goldTopics (10)Linked Datasets (6)DataCite Reuse (6)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 32%Citation Network 68%

Base Score Contribution

0.670

From this paper's citation signal

Citation Network Contribution

1.4

From 59 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 75 citers.

Fine mapping of the HLA locus in Parkinson’s disease in Europeans
npj Parkinson s Disease202174 citations40 referencesContributes 0.108
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10
Scientific Reports202160 citations58 referencesContributes 0.071
Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
Cells202315 citations44 referencesContributes 0.063
Effect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages
npj Parkinson s Disease202245 citations69 referencesContributes 0.055
LRRK2 Inhibition by PF06447475 Antagonist Modulates Early Neuronal Damage after Spinal Cord Trauma
Antioxidants20228 citations40 referencesContributes 0.055

Authors (3)

Mary K. Herrick ORCID,Malú G. Tansey ORCID,Rebecca L. Wallings ORCID

Live enrichment

PubMed:32508566 PMC:PMC7253584

National Institutes of Health

Grant: 1RF1AG057247

National Institutes of Health

Grant: 1RF1AG051514

National Institutes of Health

Grant: 1R01NS092122

Michael J. Fox Foundation for Parkinson’s Research

Grant: LRRK2 in Immunity LEAPS award

NIA NIH HHS

Grant: RF1 AG057247

NINDS NIH HHS

Grant: T32 NS096050

National Institutes of Health

Grant: 3R01NS092122-02S1

Role of HLA/MHCII in Parkinson's Disease Pathogenesis

National Institutes of Health

Grant: 7RF1AG057247-02

Role of Gut Inflammation and Immunity on Proteostasis, Noradrenergic Degeneration and AD risk

National Institutes of Health

Grant: 3RF1AG051514-01S1

Inflammation and Renin-Angiotensin System Dysfunction as risk factors for AD

goldLicense: cc-by

publisherhttps://www.frontiersin.org/articles/10.3389/fnins.2020.00443/pdf

publisherhttps://www.frontiersin.org/article/10.3389/fnins.2020.00443/full

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7253584

repositoryhttps://doaj.org/article/917fe2c3eb8b47abba0ce64a0e24b473

Europe_PMChttps://europepmc.org/articles/PMC7253584

Fields of Study

03 medical and health sciences0302 clinical medicine

Keywords

Immune functionInflammationParkinson’s DiseaseSystemic InflammationLrrk2Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neuroscience

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 2 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019737.v1figshare

Additional file 2 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019737figshare

Additional file 3 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26732620figshare

Additional file 3 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26732620.v1figshare

Additional file 1 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019592figshare

Additional file 1 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019592.v1figshare

Related Papers (10)

Key Roles of MiT Transcription Factors in Innate Immunity and Inflammation

N/A

2.2DataRank · unranked

Trends in Immunology(2020)

co-cited

10.1016/j.it.2019.12.003

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

N/A

2.1DataRank · unranked

eLife(2021)

co-cited

10.7554/elife.67900

Comparative Toxicogenomics Database (CTD): update 2021

Top 3%

5.9DataRank

Nucleic Acids Research(2020)

co-cited

10.1093/nar/gkaa891

The exposome and health: Where chemistry meets biology

N/A

1.0DataRank · unranked

Science(2020)

co-cited

10.1126/science.aay3164

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

N/A

0.828DataRank · unranked

Nature(2020)

co-cited

10.1038/s41586-020-2673-2

The In Situ Structure of Parkinson’s Disease-Linked LRRK2

Cell(2020)

co-cited

10.1016/j.cell.2020.08.004

An annotation database for chemicals of emerging concern in exposome research

Top 14%

1.5DataRank

Environment International(2021)

co-cited

10.1016/j.envint.2021.106511

Molecular characterization of projection neuron subtypes in the mouse olfactory bulb

N/A

1.4DataRank · unranked

eLife(2021)

co-cited

10.7554/elife.65445

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

Annals of Neurology(2021)

co-cited

10.1002/ana.26094

Fine-mapping of the non-coding variation driving the Caucasian LRRK2 GWAS signal in Parkinson's disease

N/A

0.645DataRank · unranked

Parkinsonism & Related Disorders(2021)

co-cited

10.1016/j.parkreldis.2020.12.016

LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (3)

Funding (9 grants)

Open Access

Topics

Linked Datasets (6)

Annotations (Europe PMC)

Related Papers (10)