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Early transcriptome changes associated with western diet induced NASH in Ldlr−/− mice points to activation of hepatic macrophages and an acute phase response

Frontiers in Nutrition(2023)10.3389/fnut.2023.1147602Source: DataRank Database

Early transcriptome changes associated with western diet induced NASH in Ldlr−/− mice points to activation of hepatic macrophages and an acute phase response is a research paper published in Frontiers in Nutrition (2023). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (2 grants)Impact (FWCI 1.20)OA: goldTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Melinda H. Spooner ORCID,Zhipeng Li ORCID,Nolan K. Newman ORCID,Christiane V. Löhr ORCID,K. Denise Apperson

Live enrichment

PubMed:37609485 PMC:PMC10440380 OpenAlex:https://openalex.org/W4385637587

National Institutes of Health

Grant: 5R01DK112360-02

Omega-3 fatty acids and the control of fatty liver disease

National Institutes of Health

Grant: 5R01DK103761-02

Gut microbiota mediates the interplay between immunity and glucose metabolism

FWCI

1.20

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.frontiersin.org/articles/10.3389/fnut.2023.1147602/pdf

GOLDhttps://www.frontiersin.org/articles/10.3389/fnut.2023.1147602/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fnut.2023.1147602/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fnut.2023.1147602/full

journalhttps://doi.org/10.3389/fnut.2023.1147602

Fields of Study

Liver Disease Diagnosis and TreatmentLipid metabolism and disordersDiet, Metabolism, and DiseaseMedicineBiologyEnvironmental Science0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Nonalcoholic fatty liver diseaseTranscriptomeSteatosisFibrosisTREM2BiologyInternal medicineInflammationEndocrinologyFatty liverCD36Hepatic fibrosisMedicineDiseaseGene expressionReceptorGeneMicrogliaGeneticsmetabolic syndromeBiological networkNASHNafldHepatic TranscriptomeNash Associated MacrophageNutrition. Foods and food supplyTX341-641Nutrition

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Early transcriptome changes associated with western diet induced NASH in Ldlr−/− mice points to activation of hepatic macrophages and an acute phase response

FAIR Checklist

Authors (11)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)