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MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing

Frontiers in Oncology(2023)10.3389/fonc.2023.1099550Source: DataRank Database

MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing is a research paper published in Frontiers in Oncology (2023). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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Linked data & code

geo gen

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 0.98)OA: goldTopics (28)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Aminah Wali,Kyle V. Butler,Yan Xiong ORCID,Joseph P. Foster,Shelsa S. Marcel ORCID

Live enrichment

PubMed:36793594 PMC:PMC9924231 OpenAlex:https://openalex.org/W4318483337

National Institutes of Health

Grant: R21CA234979, R33CA206939, R01CA166447, P30CA016086, T32CA071341, R25GM055336, T32GM067553

Hyundai Hope On Wheels

Grant: A16-0277-001

NCI NIH HHS

Grant: R21 CA234979

NIGMS NIH HHS

Grant: R25 GM055336

NCI NIH HHS

Grant: T32 CA071341

NCI NIH HHS

Grant: P30 CA016086

NCI NIH HHS

Grant: R01 CA166447

NIGMS NIH HHS

Grant: T32 GM067553

NCI NIH HHS

Grant: R33 CA206939

National Institutes of Health

Grant: 5R33CA206939-02

The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues

National Institutes of Health

Grant: 3R01CA166447-02S1

Chromatin organization and transcription factor targeting in cancer

National Institutes of Health

Grant: 3T32GM067553-05S1

UNC Predoc Training Progr in Bioinformatics/Comp Biology

National Institutes of Health

Grant: 5T32CA071341-05

CANCER CELL BIOLOGY TRAINING PROGRAM

National Institutes of Health

Grant: 3P30CA016086-42S2

Cancer Center Support Grant

National Institutes of Health

Grant: 2R25GM055336-04

UNC CH MINORITY STUDENT DEVELOPMENT PROGRAM

National Institutes of Health

Grant: 1R21CA234979-01A1

Targeting EWS-FLI1 protein stability as therapeutic strategy for Ewing sarcoma

Howard Hughes Medical Institute

V Foundation for Cancer Research

Eshelman Institute for Innovation, University of North Carolina at Chapel Hill

FWCI

0.98

Citation Percentile

0.7%

Citation Trend

2023

2024

2025

goldLicense: cc-by

journalhttps://doi.org/10.3389/fonc.2023.1099550

publisherhttps://doi.org/10.3389/fonc.2023.1099550

publisherhttps://www.frontiersin.org/articles/10.3389/fonc.2023.1099550/full

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36793594

repositoryhttps://hdl.handle.net/1805/36710

Fields of Study

Sarcoma Diagnosis and TreatmentRNA Research and SplicingRNA modifications and cancer0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

ChromatinBiologyCell biologyRNA splicingChromatin remodelingEnhancerRNAComputational biologyEpigeneticsChIA-PETGeneticsCancer researchTranscription factorGeneRNA-binding proteinsdrug discoveryRna-processingEwing Sarcoma (Es)Swi/snf (Baf) ComplexNeoplasms. Tumors. Oncology. Including cancer and carcinogensOncologyRC254-282

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being