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BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response

Biomolecules(2020)10.3390/biom10040501Source: DataRank Database

BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response is a research paper published in Biomolecules (2020). On theSindex it has a DataRank of 0. It has been cited 28 times.

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Open Access28 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: goldTopics (50)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Ajay S Potluri ORCID,Senthil K. Radhakrishnan ORCID,Janakiram R. Vangala ORCID

Live enrichment

PubMed:32224969 PMC:PMC7226130

National Institutes of Health

Grant: R01GM132396

National Institutes of Health

Grant: 3R01GM132396-05S1

Nrf1-dependent Proteotoxic Stress Response

goldLicense: cc-by

publisherhttps://www.mdpi.com/2218-273X/10/4/501/pdf?version=1585628488

publisherhttps://www.mdpi.com/2218-273X/10/4/501/pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7226130

repositoryhttps://doaj.org/article/aa7a62b50c45476ba453ce740f8d84e0

repositoryhttp://doi.org/10.3390/biom10040501

Fields of Study

0301 basic medicine03 medical and health sciencesAntineoplastic Combined Chemotherapy ProtocolsAzepinesBenzodiazepinesCell DeathCell Line, TumorDrug SynergismHeterocyclic Compounds, 4 or More RingsHumansNF-E2-Related Factor 1OligopeptidesProteasome InhibitorsTriazolesUnfolded Protein Response

MeSH Terms

Cell Line, TumorHumansAzepinesTriazolesBenzodiazepinesOligopeptidesAntineoplastic Combined Chemotherapy ProtocolsCell DeathDrug SynergismNF-E2-Related Factor 1Unfolded Protein ResponseProteasome InhibitorsHeterocyclic Compounds, 4 or More Rings

Keywords

TranscriptionCancerUnfolded protein responseProteasome inhibitorBet InhibitorsNrf1Proteasome GenesNF-E2-Related Factor 1MicrobiologyHeterocyclic Compounds, 4 or More RingsArticleBenzodiazepinesCell Line, TumorAntineoplastic Combined Chemotherapy ProtocolsHumansCell DeathDrug SynergismAzepinesTriazolesQR1-502OligopeptidesProteasome Inhibitors

Sustainable Development Goals

SDG 3: 3. Good health