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Lactate Suppresses Growth of Esophageal Adenocarcinoma Patient-Derived Organoids through Alterations in Tumor NADH/NAD+ Redox State

Biomolecules(2024)10.3390/biom14091195Source: DataRank Database

Lactate Suppresses Growth of Esophageal Adenocarcinoma Patient-Derived Organoids through Alterations in Tumor NADH/NAD+ Redox State is a research paper published in Biomolecules (2024). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 0.96)OA: goldTopics (55)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Yosuke Mitani ORCID,Tianxia Li ORCID,Uma M. Sachdeva ORCID,Samuel Flashner ORCID,Andres J. Klein–Szanto ORCID

Live enrichment

PubMed:39334961 PMC:PMC11430592 OpenAlex:https://openalex.org/W4402726372

Herbert Irving Comprehensive Cancer Center

Grant: P30CA013696

Herbert Irving Comprehensive Cancer Center

Grant: NIH P01CA098101

Herbert Irving Comprehensive Cancer Center

Grant: NIH R01DK114436

Herbert Irving Comprehensive Cancer Center

Grant: NIH R01AA026297

Herbert Irving Comprehensive Cancer Center

Grant: NIH U54 CA163004

Herbert Irving Comprehensive Cancer Center

Grant: R01 CA238433

Herbert Irving Comprehensive Cancer Center

Grant: R01 CA255298

Herbert Irving Comprehensive Cancer Center

Grant: PF-23 1151788-01-DMC

Herbert Irving Comprehensive Cancer Center

Grant: NIH 5T32CA265828-02

Herbert Irving Comprehensive Cancer Center

Grant: NIH L30CA264714

NIDDK NIH HHS

Grant: P30 DK132710

National Institutes of Health

Grant: 3U54CA163004-07S1

The Role of the Microenvironment in Barrett's Esophagus

National Institutes of Health

Grant: 1P30DK132710-01

The Columbia University Digestive and Liver Disease Research Center

National Institutes of Health

Grant: 2R01AA026297-07A1

Aldh2 and epithelial homeostasis and pathobiology

National Institutes of Health

Grant: 1R01CA255298-01

The Role of the Microbiome and Notch Signaling in Esophageal Adenocarcinoma

National Institutes of Health

Grant: 5P01CA098101-07

Molecular Biology/Gene Expression Core

National Institutes of Health

Grant: 5R01CA238433-02

The Oral Microbiome for the Detection of Barretts Esophagus

National Institutes of Health

Grant: 3P30CA013696-21S1

CANCER CENTER CORE SUPPORT GRANT

National Institutes of Health

Grant: 5R01DK114436-06

Autophagy and esophageal tissue remodeling in EoE

National Institutes of Health

Grant: 5T32CA265828-02

Genome and Epigenome Integrity In Cancer

FWCI

0.96

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2218-273X/14/9/1195/pdf?version=1727166435

publisherhttps://www.mdpi.com/2218-273X/14/9/1195/pdf?version=1727166435

publisherhttps://www.mdpi.com/2218-273X/14/9/1195/pdf

journalhttps://doi.org/10.3390/biom14091195

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39334961

Fields of Study

Epigenetics and DNA MethylationPancreatic and Hepatic Oncology ResearchEsophageal Cancer Research and TreatmentEsophageal NeoplasmsHumansAdenocarcinomaOxidation-ReductionOrganoidsNADLactic AcidCell ProliferationGlycolysisBarrett EsophagusTumor MicroenvironmentAdenocarcinoma Of Esophagus

MeSH Terms

AdenocarcinomaBarrett EsophagusEsophageal NeoplasmsGlycolysisHumansNADOrganoidsOxidation-ReductionLactic AcidCell ProliferationTumor Microenvironment

Keywords

GlycolysisNAD+ kinaseBarrett's esophagusWarburg effectAdenocarcinomaCancer researchOrganoidBiologyChemistryMetabolismBiochemistryCell biologyCancerEnzymeGeneticsLactateEsophageal adenocarcinomaTumor MicroenvironmentEsophageal NeoplasmsNADMicrobiologyQR1-502ArticleOrganoidsBarrett EsophagusHumansLactic AcidOxidation-ReductionCell Proliferation

Sustainable Development Goals

SDG 0: Good health and well-being