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Mitochondrial Uncoupler, 2,4-Dinitrophenol, Reduces Spinal Cord Paralysis and Retinal Ganglion Cell Loss in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Biomolecules(2025)10.3390/biom15020189Source: DataRank Database

Mitochondrial Uncoupler, 2,4-Dinitrophenol, Reduces Spinal Cord Paralysis and Retinal Ganglion Cell Loss in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis is a research paper published in Biomolecules (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (4 grants)Impact (FWCI 1.52)OA: goldTopics (35)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Reas S. Khan,Suad Abd Alhadi,Kimberly Dine ORCID,John G. Geisler,Brahim Chaqour ORCID

Live enrichment

PubMed:40001492 PMC:PMC11852757 OpenAlex:https://openalex.org/W4406903502

National Institutes of Health Grant

Grant: EY019014

Paul and Evanina Mackall Foundation Trust

Grant: n/a

NEI NIH HHS

Grant: R01 EY019014

Research To Prevent Blindness

Grant: unrestricted grant

FWCI

1.52

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2218-273X/15/2/189/pdf?version=1738076347

publisherhttps://www.mdpi.com/2218-273X/15/2/189/pdf?version=1738076347

publisherhttps://www.mdpi.com/2218-273X/15/2/189/pdf

journalhttps://doi.org/10.3390/biom15020189

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40001492

Fields of Study

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration MechanismsOcular Diseases and Behçet’s Syndrome

MeSH Terms

AnimalsDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleMice, Inbred C57BLMitochondriaMultiple SclerosisOptic NeuritisParalysisRetinal Ganglion CellsSpinal CordUncoupling AgentsReactive Oxygen Species2,4-DinitrophenolMice

Keywords

Multiple sclerosisOptic neuritisExperimental autoimmune encephalomyelitisMedicineRetinal ganglion cellOptic nerveSpinal cordParalysisPathologyAnesthesiaImmunologyOphthalmologySurgeryDinitrophenolEAERgc NeuroprotectionMitochondrial Uncoupling Agent

Sustainable Development Goals

SDG 0: Good health and well-being

Mitochondrial Uncoupler, 2,4-Dinitrophenol, Reduces Spinal Cord Paralysis and Retinal Ganglion Cell Loss in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

FAIR Checklist

Authors (8)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)