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Ras Pathway Activation and MEKi Resistance Scores Predict the Efficiency of MEKi and SRCi Combination to Induce Apoptosis in Colorectal Cancer

Cancers(2022)10.3390/cancers14061451Source: DataRank Database

Ras Pathway Activation and MEKi Resistance Scores Predict the Efficiency of MEKi and SRCi Combination to Induce Apoptosis in Colorectal Cancer is a research paper published in Cancers (2022). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Scored on demand from live citation data

Open Access4 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.37)OA: goldTopics (27)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Shilpa Gupta ORCID,Mingli Yang ORCID,Lance Pflieger ORCID,Malini Rajan ORCID,Heiman Wang

Live enrichment

PubMed:35326598 PMC:PMC8945886 OpenAlex:https://openalex.org/W4220918843

National Institutes of Health

Grant: UH3CA227955

NCI NIH HHS

Grant: R21 CA255312

NCI NIH HHS

Grant: R21 CA256372

FWCI

0.37

Citation Percentile

0.6%

Citation Trend

2022

2023

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/2072-6694/14/6/1451/pdf?version=1646999211

publisherhttps://www.mdpi.com/2072-6694/14/6/1451/pdf?version=1646999211

publisherhttps://www.mdpi.com/2072-6694/14/6/1451/pdf

journalhttps://doi.org/10.3390/cancers14061451

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35326598

Fields of Study

Colorectal Cancer Treatments and StudiesMelanoma and MAPK PathwaysGenetic factors in colorectal cancer

Keywords

Colorectal cancerMedicineTrametinibMEK inhibitorCancer researchGene signatureApoptosisCancerSignal transductionGeneInternal medicineMAPK/ERK pathwayBiologyGene expressionCell biologyGeneticsDrug resistanceBiomarkersColorectal Cancer (Crc)Mek InhibitionSrc InhibitionConsensus Molecular Subtype (Cms)Drugs Sensitivity SelectionGene Signature Score

Sustainable Development Goals

SDG 0: Good health and well-being

Ras Pathway Activation and MEKi Resistance Scores Predict the Efficiency of MEKi and SRCi Combination to Induce Apoptosis in Colorectal Cancer

FAIR Checklist

Authors (9)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)