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Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis

Cancers(2023)10.3390/cancers15030967Source: DataRank Database

Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis is a research paper published in Cancers (2023). On theSindex it has a DataRank of 0.165. It has been cited 2 times.

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0.165DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 0.18)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.165

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (9)

Taimoor Khan ORCID,Santiago Serrano ORCID,Anthony Rodriguez-Lemus,Chananat Klomsiri,Tim-Mathis Beutel ORCID

Live enrichment

PubMed:36765925 PMC:PMC9913803 OpenAlex:https://openalex.org/W4319082945

California Breast Cancer Research Program

Grant: A135706

NCI NIH HHS

Grant: K22 CA226365

Wellcome Trust

Grant: 214342/Z/18/Z

Deutsche Forschungsgesellschaft (DFG, German Research Foundation)

Grant: SFB1403-414786233

Medical Research Council

Grant: MR/S00811X/1

Defining the roles and functional interdependencies of linear ubiquitin-related deubiquitinases and LUBAC in TNFR1 signalling

Deutsche Forschungsgesellschaft (DFG, German Research Foundation)

Grant: SFB1399

Cancer Research UK

Grant: 27323

Deutsche Forschungsgesellschaft (DFG, German Research Foundation)

Grant: SFB1530-455784452

Cancer Research UK Programme

Grant: A27323

Wellcome Trust

Grant: 214342

The role of cell death in inflammation and inflammation-related disorders

National Institutes of Health

Grant: 1K22CA226365-01A1

Identification of Novel Gene Regulatory Interactions Driving the Immune Evasion Program Through Transcriptional Activation of CD47 in Cancer

Alexander von Humboldt Foundation Professorship

Wellcome Trust

FWCI

0.18

Citation Percentile

0.4%

Citation Trend

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/2072-6694/15/3/967/pdf?version=1675404918

publisherhttps://www.mdpi.com/2072-6694/15/3/967/pdf?version=1675404918

journalhttps://doi.org/10.3390/cancers15030967

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36765925

repositoryhttps://discovery.ucl.ac.uk/id/eprint/10167125/

Fields of Study

interferon and immune responsesCell death mechanisms and regulationCytokine Signaling Pathways and Interactions0301 basic medicine03 medical and health sciences

Keywords

Downregulation and upregulationAutocrine signallingCancer cellInterferonParacrine signallingApoptosisCancer researchCell biologyEnhancerIntracellularBiologyCancerTumor necrosis factor alphaCytokineChemistryImmunologyCell cultureGene expressionReceptorGeneBiochemistryGeneticsLung cancerBreast cancerTRAILEnhancer ClustersIntracellular Protein AccumulationEXPRESSIONScience & TechnologyMAPATUMUMABDEATHDEPENDENCIESArticleACTIVATIONOncologyHUMAN T-CELLSLIGAND TRAILLife Sciences & BiomedicineHUMAN MONOCLONAL-ANTIBODY

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being